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原发性高血压患者高尿酸血症患病率及其影响因素分析

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目的 调查原发性高血压患者高尿酸血症(HUA)的患病情况并分析其可能的影响因素。方法 选取2022年9月至 12月在武汉市第四医院住院治疗的265 例原发性高血压患者进行横断面研究。按血清尿酸(SUA)水平将其分为HUA组和非HUA组,分析原发性高血压患者发生HUA的可能影响因素。结果 265 例原发性高血压患者的HUA总患病率为30。19%,男性患病率高于女性(P<0。001)。不同年龄段原发性高血压患者的HUA患病率比较,差异有统计学意义(P<0。001)。两组年龄、性别、体质指数(BMI)、BMI分级、腰围、高密度脂蛋白胆固醇(HDL-C)、甘油三酯(TG)水平比较,差异有统计学意义(P<0。05)。Spearman相关性检验显示,原发性高血压患者的SUA水平与HDL-C呈负相关,与TG、总胆固醇(TC)呈正相关(P<0。05)。Logistic回归分析结果显示,年龄、性别、BMI和TG是原发性高血压患者发生HUA的影响因素(P<0。05)。结论 原发性高血压患者HUA患病率较高,且存在性别差异;影响原发性高血压患者发生HUA的因素有年龄、性别、BMI和TG。
Analysis of prevalence and influencing factors of hyperuricemia in patients with essential hypertension
Objective To investigate the preva lence of hyperuricemia(HUA)in patients with essential hypertension and analyze its possible influencing factors.Methods A cross-sectional study was conducted on 265 patients with essential hypertension who were hospitalized in the Wuhan Fourth Hospital from September to December 2022.According to the level of serum uric acid(SUA),the patients were divided into HUA group and non-HUA group,and the possible influencing factors of HUA in patients with essential hypertension were analyzed.Results The total prevalence of HUA in 265 patients with essential hypertension was 30.19%,and the prevalence of men was higher than that of women(P<0.001).There was a statistically significant difference in the prevalence of HUA among patients with essential hypertension in different age groups(P<0.001).There were statistically significant differences in age,gender,body mass index(BMI),BMI classification,waist circumference,and the levels of high-density lipoprotein cholesterol(HDL-C)and triacylglycerol(TG)between the two groups(P<0.05).Spearman correlation test showed that SUA level in patients with essential hypertension was negatively correlated with HDL-C and positively correlated with TG and total cholesterol(TC)(P<0.05).Logistic regression analysis showed that age,gender,BMI and TG were the influencing factors of HUA in patients with essential hypertension(P<0.05).Conclusion The prevalence of HUA in patients with essential hypertension is high,and there are gender differences;the factors affecting the occurrence of HUA in patients with essential hypertension are age,gender,BMI and TG.

hypertensionhyperuricemiaprevalenceinfluencing factor

朱倩茹、邹武松

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江汉大学,湖北 武汉,430056

武汉市第四医院,湖北 武汉,430000

高血压 高尿酸血症 患病率 影响因素

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(14)
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