首页|不同手术时机对结肠镜下支架置入术后择期行腹腔镜结直肠癌根治术治疗结直肠癌合并肠梗阻患者预后的影响

不同手术时机对结肠镜下支架置入术后择期行腹腔镜结直肠癌根治术治疗结直肠癌合并肠梗阻患者预后的影响

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目的 探究不同手术时机对结肠镜下支架置入术后择期行腹腔镜结直肠癌根治术治疗结直肠癌合并肠梗阻患者预后的影响。方法 选取 2021 年 10 月至 2023 年 3 月我院收治的 76 例结直肠癌合并肠梗阻患者作为研究对象,给予结肠镜下支架置入术治疗,并于术后行腹腔镜结直肠癌根治术。根据腹腔镜手术时机将其分为A组(n=20,术后 3~6 d)、B组(n=19,术后 7~9 d)、C组(n=21,术后 10~14 d)、D组(n=16,术后>14 d)。比较四组的治疗效果。结果 四组的手术时间、术中出血量、淋巴结清扫数量、住院时间、术后肛门排气时间比较,差异无统计学意义(P>0。05)。治疗后,四组的胃动素(MTL)、胃泌素(GAS)水平均显著降低(P<0。05);治疗后,D组的MTL、GAS水平高于A、B、C组(P<0。05)。四组的术后并发症总发生率比较,差异无统计学意义(P>0。05)。结论 不同腹腔镜手术时机的选择对结肠镜下支架置入术后择期行腹腔镜结直肠癌根治术治疗结直肠癌合并肠梗阻患者均有显著疗效,且安全性高;术后>14 d行腹腔镜手术治疗对患者胃肠功能改善效果更明显,临床可结合患者实际情况合理选择手术时机。
Effect of different surgical timing on the prognosis of patients with colorectal cancer complicated with intestinal obstruction treated by laparoscopic radical resection of colorectal cancer after stent implantation under colonoscopy
Objective To explore the effect of different surgical timing on the prognosis of patients with colorectal cancer complicated with intestinal obstruction treated by laparoscopic radical resection of colorectal cancer after stent implantation under colonoscopy.Methods A total of 76 patients with colorectal cancer complicated with intestinal obstruction admitted in our hospital from October 2021 to March 2023 were selected as the research objects.The patients were treated with stent implantation under colonoscopy and underwent laparoscopic radical resection of colorectal cancer after operation.According to the timing of laparoscopic surgery,the patients were divided into group A(n=20,3-6 d after operation),group B(n=19,7-9 d after operation),group C(n=21,10-14 d after operation),group D(n=16,>14 d after operation).The therapeutic effects were compared among the four groups.Results There were no significant differences in operation time,intraoperative blood loss,number of lymph node dissection,hospitalization time and postoperative anal exhaust time among the four groups(P>0.05).After treatment,the levels of motilin(MTL),gastrin(GAS)in the four groups were significantly decreased(P<0.05);after treatment,the levels of MTL and GAS in the group D were higher than those in the group A,B and C(P<0.05).There was no significant difference in the total incidence of postoperative complications among the four groups(P>0.05).Conclusion The choice of different laparoscopic surgery timing has significant efficacy and high safety for patients with colorectal cancer complicated with intestinal obstruction treated by laparoscopic radical resection of colorectal cancer after stent implantation under colonoscopy;laparoscopic surgery>14 d after operation has a more obvious effect on the improvement of gastrointestinal function,the surgical timing can be reasonably selected according to the actual situation of patients.

laparoscopysurgical timingcolonoscopystent implantationselective treatmentcolorectal cancerintestinal obstruction

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南阳市中心医院普通外科胃肠二病区,河南 南阳,473000

腹腔镜 手术时机 结肠镜 支架置入 择期治疗 结直肠癌 肠梗阻

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(14)
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