Effect of different surgical timing on the prognosis of patients with colorectal cancer complicated with intestinal obstruction treated by laparoscopic radical resection of colorectal cancer after stent implantation under colonoscopy
Objective To explore the effect of different surgical timing on the prognosis of patients with colorectal cancer complicated with intestinal obstruction treated by laparoscopic radical resection of colorectal cancer after stent implantation under colonoscopy.Methods A total of 76 patients with colorectal cancer complicated with intestinal obstruction admitted in our hospital from October 2021 to March 2023 were selected as the research objects.The patients were treated with stent implantation under colonoscopy and underwent laparoscopic radical resection of colorectal cancer after operation.According to the timing of laparoscopic surgery,the patients were divided into group A(n=20,3-6 d after operation),group B(n=19,7-9 d after operation),group C(n=21,10-14 d after operation),group D(n=16,>14 d after operation).The therapeutic effects were compared among the four groups.Results There were no significant differences in operation time,intraoperative blood loss,number of lymph node dissection,hospitalization time and postoperative anal exhaust time among the four groups(P>0.05).After treatment,the levels of motilin(MTL),gastrin(GAS)in the four groups were significantly decreased(P<0.05);after treatment,the levels of MTL and GAS in the group D were higher than those in the group A,B and C(P<0.05).There was no significant difference in the total incidence of postoperative complications among the four groups(P>0.05).Conclusion The choice of different laparoscopic surgery timing has significant efficacy and high safety for patients with colorectal cancer complicated with intestinal obstruction treated by laparoscopic radical resection of colorectal cancer after stent implantation under colonoscopy;laparoscopic surgery>14 d after operation has a more obvious effect on the improvement of gastrointestinal function,the surgical timing can be reasonably selected according to the actual situation of patients.