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小续命汤治疗中风后疲劳的临床研究及对Hcy水平的调节作用

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目的 观察小续命汤治疗中风后疲劳(PSF)的效果及对中风二级预防的价值.方法 选取2020 年10月至2021年 12 月于陕西省中医医院针灸三科接受治疗的 72 例PSF患者为研究对象,采用随机数字表法将其分为对照组、治疗组,各 36 例.对照组给予西医基础治疗及针灸康复治疗,治疗组在对照组基础上增加小续命汤治疗.比较两组的治疗效果.结果 治疗前,两组的神经功能缺损程度、疲劳严重程度量表(FSS)及精力评分比较,差异无统计学意义(P>0.05);治疗 4 周后,两组的神经功能缺损程度、FSS评分低于治疗前,精力评分高于治疗前,差异具有统计学意义(P<0.05);治疗4 周后,治疗组的FSS评分低于对照组,精力评分高于对照组,差异具有统计学意义(P<0.05).治疗前,两组的同型半胱氨酸(Hcy)水平比较,差异无统计学意义(P>0.05);治疗 4 周后,两组的Hcy水平低于治疗前,且治疗组低于对照组,差异具有统计学意义(P<0.05).结论 小续命汤治疗PSF的效果显著,且有助于降低Hcy水平,对中风的二级预防有重要意义.
Clinical study of Xiaoxuming decoction in the treatment of post-stroke fatigue and its regulating effect on Hcy level
Objective To observe the effect of Xiaoxuming decoction in the treatment of post-stroke fatigue(PSF)and its secondary prevention value for stroke.Methods A total of 72 patients with PSF who were treated in the No.3 acupuncture and moxibustion department of Shaanxi Provincial Hospital of C hinese Medicine from October 2020 to December 2021 were selected as the research objects.The patients were divided into control group and treatment group by random number table method,with 36 cases in each group.The control group was given basic western medicine treatment and acupuncture rehabilitation treatment,and the treatment group was treated with Xiaoxuming decoction on the basis of the control group.The therapeutic effects of the two groups were compared.Results Before treatment,there were no significant differences in the scores of neurological deficit degree,Fatigue Severity Scale(FSS)and energy between the two groups(P>0.05);after 4 weeks of treatment,the scores of neurological deficit degree and FSS in the two groups were lower than those before treatment,the energy score was higher than that before treatment,the differences were statistically significant(P<0.05);after 4 weeks of treatment,the FSS score of the treatment group was lower than that of the control group,and the energy score was higher than that of the control group,the differences were statistically significant(P<0.05).Before treatment,there was no significant difference in homocysteine(Hcy)level between the two groups(P>0.05);after 4 weeks of treatment,the levels of Hcy in the two groups was lower than that before treatment,and that in the treatment group was lower than the control group,the difference was statistically significant(P<0.05).Conclusion Xiaoxuming decoction in the treatment of PSF has significant effect,and it is helpful to reduce the level of Hcy,which is of great significance to the secondary prevention of stroke.

post-stroke fatigueXiaoxuming decoctionhomocysteine

张香妮、宋瑞

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陕西省中医医院,陕西 西安,710003

中风后疲劳 小续命汤 同型半胱氨酸

国家中医药局重大疑难疾病中西医临床协作试点项目西安市科技计划

国中医药办医政发[2018]3号2017122SF/YX01614

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(14)
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