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乳腺癌患者术后并发上肢淋巴水肿的现状及影响因素分析

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目的 调查乳腺癌患者术后并发上肢淋巴水肿的现状及其影响因素.方法 采用横断面整群抽样选取2021 年 2 月至 2023 年 8 月我院收治的 121 例乳腺癌术后患者作为研究对象.收集患者的临床资料,采用多因素Logistic回归分析影响乳腺癌患者术后并发上肢淋巴水肿的因素.结果 121 例乳腺癌患者中,术后并发上肢淋巴水肿 23 例,发生率为 19.01%.根据术后是否并发上肢淋巴水肿将患者分为发生组(n=23)与未发生组(n=98).发生组的年龄大于未发生组,体重指数(BMI)≥24 kg/m2 占比、有腋窝淋巴结清扫占比、清扫淋巴结数、有术后辅助放疗占比及有术后愈合并发症占比高于未发生组(P<0.05).多因素Logistic回归分析结果显示,年龄、BMI、腋窝淋巴结清扫、清扫淋巴结数、术后辅助放疗及术后愈合并发症是乳腺癌患者术后并发上肢淋巴水肿的危险因素(P<0.05).结论 乳腺癌患者术后上肢淋巴水肿发生率较高,年龄、BMI、腋窝淋巴结清扫、清扫淋巴结数、术后辅助放疗及术后愈合并发症均可能影响乳腺癌患者术后上肢淋巴水肿发生情况,临床应及早实施针对性策略加以控制.
Analysis of current situation and influencing factors of upper limb lymphedema in patients with breast cancer after operation
Objective To investigate the current situation and influencing factors of upper limb lymphedema in patients with breast cancer after operation.Methods A total of 121 patients with breast cancer who were admitted in our hospital from February 2021 to August 2023 were selected as the study objects by cross-sectional cluster sampling.The clinical data of the patients were collected,and multivariate Logistic regression analysis was used to analyze the influencing factors of upper limb lymphedema in breast cancer patients after operation.Results Among 121 patients with breast cancer,23 patients had upper limb lymphedema after operation,with an incidence of 19.01%.The patients were divided into occurrence group(n=23)and non-occurrence group(n=98)according to whether upper limb lymphedema occurred after operation.The age of the occurrence group was older than that of the non-occurrence group,and the proportion of body mass index(BMI)≥24 kg/m2,the proportion of axillary lymph node dissection,the number of lymph nodes dissected,the proportion of postoperative adjuvant radiotherapy and the proportion of postoperative healing complications were higher than those of the non-occurrence group(P<0.05).Multivariate Logistic regression analysis results showed that age,BMI,axillary lymph node dissection,number of lymph nodes dissected,postoperative adjuvant radiotherapy and postoperative healing complications were risk factors for upper limb lymphedema in patients with breast cancer after operation(P<0.05).Conclusion The incidence of upper limb lymphedema in breast cancer patients after operation is high.Age,BMI,axillary lymph node dissection,number of lymph nodes dissected,postoperative adjuvant radiotherapy and postoperative healing complications may affect the occurrence of upper limb lymphedema in breast cancer patients after operation,and targeted strategies should be implemented as early as possible to control it in clinic.

breast cancerupper limb lymphedemaLogistic regression modelsurgical treatment

陈会娜

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濮阳市第五人民医院肿瘤科,河南 濮阳,457000

乳腺癌 上肢淋巴水肿 Logistic回归模型 手术治疗

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(15)
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