Relationship between regional cerebral oxygen saturation and postoperative cognitive dysfunction in elderly patients undergoing laparoscopic radical gastrectomy for gastric cancer
Objective To investigate and analyze the relationship between regional cerebral oxygen saturation(rSO2)and postoperative cognitive dysfunction in elderly patients undergoing laparoscopic radical gastrectomy for gastric cancer.Methods A total of 86 elderly patients who underwent laparoscopic radical gastrectomy for gastric cancer from June 2019 to June 2023 were selected as the research objects.According to whether cognitive dysfunction occurred,the patients were divided into cognitive dysfunction group and normal cognitive function group.The general data and rSO2 of the two groups were compared;the relationship between rSO2 and postoperative cognitive dysfunction was analyzed.Results Among the 86 patients,there were 31 patients with cognitive dysfunction and 55 patients without cognitive dysfunction;from 60 min of pneumoperitoneum(T2)to recovery(T5),the rSO2 in the cognitive dysfunction group was lower than that in the normal cognitive function group(P<0.05).There were significant differences in age,hypertension,diabetes,hypercholesterolemia,rSO2,and intraoperative mean artery pressure(MAP)between the two groups(P<0.05).Multivariate Logistic regression analysis results showed that age>70 years,hypertension,diabetes,hypercholesterolemia,low rSO2,and high intraoperative MAP were independent risk factors for postoperative cognitive dysfunction in elderly patients undergoing laparoscopic radical gastrectomy for gastric cancer(P<0.05).Conclusion rSO2 is closely related to postoperative cognitive dysfunction in elderly patients undergoing laparoscopic radical gastrectomy for gastric cancer,low rSO2 can easily lead to postoperative cognitive dysfunction.At the same time,age,hypertension,diabetes,hypercholesterolemia,and intraoperative MAP are also related to postoperative cognitive dysfunction.
laparoscopic radical gastrectomy for gastric cancerregional cerebral oxygen saturationcognitive dysfunctiongastric cancer
万方数据
维普
