Effects of prophylactic terminal ileostomy on inflammatory indexes and anal function in patients undergoing laparoscopic radical anal preservation surgery for low rectal cancer
Objective To analyze the effect of prophylactic terminal ileostomy on the prognosis of patients undergoing laparoscopic radical anal preservation surgery for low rectal cancer.Methods A total of 86 patients with low rectal cancer who underwent laparoscopic radical anal preservation surgery in our hospital from February 2021 to February 2023 were selected as the research objects and randomly divided into transverse colon group(43 cases,prophylactic transverse colostomy)and terminal ileum group(43 cases,prophylactic terminal ileostomy).The therapeutic effects of the two groups were compared.Results There were no significant differences in operation time and intraoperative blood loss between the two groups(P>0.05);the exhaust time,intestinal peristalsis time,first defecation time and hospitalization time in the terminal ileum group were significantly shorter than those in the transverse colon group(P<0.05).The total incidence of postoperative complications in the terminal ileum group was significantly lower than that in the transverse colon group(P<0.05).At discharge,1 month and 3 months after operation,the Wexner score of the terminal ileum group was significantly lower than that of the transverse colon group(P<0.05).After operation,the levels of interferon-γ(IFN-γ),prostaglandin E2(PGE2),myeloperoxidase(MPO)and high-sensitivity C-reactive protein(hs-CRP)in the terminal ileum group were significantly lower than those in the transverse colon group(P<0.05).At discharge,the maximum anal resting pressure and maximum anal systolic pressure of the terminal ileum group were significantly higher than those of the transverse colon group,and the maximum rectal resting pressure was significantly lower than that of the transverse colon group(P<0.05).Conclusion Prophylactic terminal ileostomy in patients undergoing laparoscopic radical anal preservation surgery for low rectal cancer can effectively guarantee the prognosis.
laparoscopic radical anal preservation surgery for low rectal cancerprophylactic terminal ileostomyrectal surgeryanal function
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