Application effect of laser peripheral iridectomy in patients with primary acute angle-closure glaucoma and its influences on intraocular pressure and visual acuity
Objective To investigate the application effect of laser peripheral iridectomy in patients with primary acute angle-closure glaucoma and its influences on intraocular pressure and visual acuity.Methods A total of 80 patients(86 eyes)with primary acute angle-closure glaucoma from October 2020 to October 2022 were randomly selected as the research objects.All patients were treated with laser peripheral iridectomy.The intraocular pressure,visual acuity,angle closure and corneal endothelial cell indexes were observed before and after operation.Results After operation,the intraocular pressure of patients was lower than that before operation,and the visual acuity level was higher than that before operation(P<0.05).After operation,the anterior chamber angle(ACA),anterior chamber volume(ACV)and peripheral anterior chamber depth(PACD)were significantly bigger than those before operation(P<0.05);there was no significant difference in central anterior chamber depth(CACD)between preoperative and postoperative(P>0.05).There were no significant differences in the average corneal endothelial cell area(AVE),maximum cell area(MAX),minimum cell area(MIN),cell density(CD),coefficient of variation(CV)and standard deviation of cell area(SD)between preoperative and postoperative(P>0.05).Conclusion Early laser peripheral iridectomy in patients with primary acute angle-closure glaucoma has a significant effect on reducing intraocular pressure,and can also improve visual acuity and angle closure,which has less damage to corneal endothelial cells and higher safety.