首页|2014-2020年整形烧伤科皮肤软组织感染患者的病原菌特点和耐药性分析

2014-2020年整形烧伤科皮肤软组织感染患者的病原菌特点和耐药性分析

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目的 分析2014-2020 年整形烧伤科皮肤软组织感染(SSTI)患者的病原菌特点及其耐药性.方法 回顾性分析2014 年1月至2020年 12月收治的644 例SSTI住院患者的临床资料和病原学检验结果.结果 共分离 976 株病原菌,其中革兰氏阳性菌 445 株,以金黄色葡萄球菌为主要致病菌,该菌对青霉素、红霉素的耐药率较高;革兰氏阴性菌 500 株,以铜绿假单胞菌为主要致病菌,该菌对氨苄西林舒巴坦、复方磺胺甲噁唑的耐药率较高.SSTI中院内获得性感染以革兰氏阴性菌为主,社区获得性感染以革兰氏阳性菌为主.多重耐药菌(MDRO)以耐甲氧西林金黄色葡萄球菌(MRSA)及耐碳青霉烯类肠杆菌科细菌(CRE)为主.结论 整形烧伤科收治的SSTI病原菌种类繁多,耐药性较高,应在药物敏感试验指导下合理用药.
Analysis of pathogen characteristics and drug resistance of patients with skin and soft tissue infections in plastic and burn department from 2014 to 2020
Objective To analyze the pathogen characteristics and drug resistance of patients with skin and soft tissue infections(SSTI)in plastic and burn department from 2014 to 2020.Methods The clinical data and etiological test results of 644 patients with SSTI admitted from January 2014 to December 2020 were retrospectively analyzed.Results A total of 976 strains of pathogens were isolated,including 445 strains of Gram-positive bacteria,with Staphylococcus aureus as the main pathogen.The pathogen had a higher drug resistance rate to penicillin and erythromycin.There were 500 strains of Gram-negative bacteria,with Pseudomonas aeruginosa as the main pathogen.The pathogen had a higher drug resistance rate to ampicillin sulbactam and compound sulfamethoxazole.The nosocomial infection in SSTI was mainly Gram-negative bacteria,and the community-acquired infection was mainly Gram-positive bacteria.Multidrug-resistant organism(MDRO)were mainly methicillin-resistant Staphylococcus aureus(MRSA)and carbapenem-resistant Enterobacteriaceae(CRE).Conclusion There are many kinds of SSTI pathogens in the plastic and burn department,and the drug resistance is high.Rational use of drugs should be guided by drug sensitivity test.

plastic and burn departmentskin and soft tissue infectionspathogendrug resistance

赵旭、张永祥、严向明、张卫红、李占结

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江苏省人民医院/南京医科大学第一附属医院感染管理处,江苏 南京,210029

苏州市疾病预防控制中心应急(综合业务)办公室,江苏 苏州,215000

苏州大学附属儿童医院院长办公室,江苏 苏州,215002

整形烧伤科 皮肤软组织感染 病原菌 耐药性

国家自然科学基金青年基金培育计划立项项目(2022)江苏省医院协会医院管理创新研究课题(2023)江苏省人民医院/南京医科大学第一附属医院"优秀中青年人才支持计划"培养项目(第三期)

PY2022017JSYGY-3-2023-559YNRCQN0314

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(17)