Effect of acetylcysteine combined with procaterol and azithromycin sequential therapy on Mycoplasma pneumoniae pneumonia in children and its influences on inflammatory factors
Objective To investigate the effect of acetylcysteine combined with procaterol and azithromycin sequential therapy on Mycoplasma pneumoniae pneumonia in children and its influences on inflammatory factors.Methods A total of 84 children with Mycoplasma pneumoniae pneumonia who were treated in our hospital from June 2020 to June 2022 were selected as the research objects.The children were randomly divided into control group and observation group,with 42 cases in each group.The control group was given procaterol and azithromycin sequential therapy,and the observation group was treated with acetylcysteine on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was 90.48%,which was higher than 71.43%in the control group(P<0.05).After treatment,the levels of interferon-γ(IFN-γ)and interleukin-8(IL-8)in the observation group were lower than those in the control group,and the level of interleukin-10(IL-10)was higher than that in the control group(P<0.05).After treatment,the partial pressure of oxygen(PaO2),oxygen saturation of blood(SaO2),forced vital capacity(FVC)and peak expiratory flow(PEF)were higher than those in the control group(P<0.05).Conclusion The acetylcysteine combined with procaterol and azithromycin sequential therapy for Mycoplasma pneumoniae pneumonia in children can not only improve the clinical treatment effect,but also effectively inhibit inflammatory factors,reduce inflammatory damage,and has a positive effect on improving ventilation and lung function in children.It is worth promoting.
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