Clinical effect of phacoemulsification in the treatment of patients with cataract combined with Fuchs corneal endothelial dystrophy
Objective To observe the clinical effect of phacoemulsification in the treatment of patients with cataract combined with Fuchs corneal endothelial dystrophy.Methods From January 2014 to December 2020,20 patients who were diagnosed as cataract with Fuchs corneal endothelial dystrophy and underwent phacoemulsification combined with intraocular lens implantation in our hospital were included in experimental group,and 20 patients who were diagnosed with cataract and normal cornea at the same time and underwent phacoemulsification combined with intraocular lens implantation were included in control group.The visual acuity and intraocular pressure of the two groups before and after operation were examined,and the best corrected visual acuity was recorded;the corneal condition was observed by slit lamp microscope;the morphology of corneal endothelial cells was observed by corneal laser confocal microscope,and the density of corneal endothelial cells,the proportion of hexagonal cells and the loss rate of corneal endothelial cells were calculated.Results The best corrected visual acuity of the two groups was significantly improved after operation;there were no obvious abnormalities in intraocular pressure before and after operation in the two groups.At 3 months after operation,the corneal endothelial cell density and the proportion of hexagonal cells in the experimental group were lower than those in the control group(P<0.05);the corneal endothelial cell loss rate in the experimental group was higher than that in the control group(P<0.001).Conclusion Phacoemulsification is effective in patients with cataract combined with Fuchs corneal endothelial dystrophy,but the degree of endothelial cell loss is higher than that in patients with cataract with normal cornea.
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