首页|超早期小骨窗微创脑出血清除术治疗脑出血的效果及对患者术后功能恢复与生活自理能力的影响

超早期小骨窗微创脑出血清除术治疗脑出血的效果及对患者术后功能恢复与生活自理能力的影响

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目的 分析超早期小骨窗微创脑出血清除术治疗脑出血的临床效果。方法 选择2019年2月至2022年2月收治的80例脑出血患者为研究对象,入院后患者均接受小骨窗微创脑出血清除术治疗,根据入院先后顺序将其分为对照组(n=40,发病6~24 h内手术)和研究组(n=40,发病6 h内手术)。比较两组的临床疗效、血清指标、血流动力学指标、脑代谢指标、神经功能及生活自理能力。结果 研究组的治疗总有效率显著高于对照组(P<0。05)。治疗后,研究组的血管内皮生长因子(VEGF)、血管生成素-1(Ang-1)、血管升压素(AVP)水平显著低于对照组,血管内皮生长因子受体-1(FLK-1)水平显著高于对照组(P<0。05)。治疗后,研究组的收缩期峰值流速(PSV)、平均血流速度(Vm)、N-乙酰天冬氨酸(NAA)/肌酸复合物(Cr)显著高于对照组,胆碱复合物(Cho)/Cr显著低于对照组(P<0。05)。治疗后,研究组的美国国立卫生院卒中量表(NIHSS)评分显著低于对照组,改良Barthel指数(MBI)评分显著高于对照组(P<0。05)。结论 超早期小骨窗微创脑出血清除术治疗脑出血效果显著,能够改善血清指标、脑部循环及代谢,促进患者的神经功能恢复以及生活自理能力提高。
Effect of ultra-early small bone window minimally invasive cerebral hemorrhage removal on cerebral hemorrhage and its influences on postoperative functional recovery and self-care ability of patients
Objective To analyze the clinical effect of ultra-early small bone window minimally invasive cerebral hemorrhage removal in the treatment of cerebral hemorrhage.Methods A total of 80 patients with cerebral hemorrhage admitted from February 2019 to February 2022 were selected as the research objects.After admission,all patients received minimally invasive cerebral hemorrhage removal with small bone window.According to the order of admission,the patients were divided into control group(n=40,surgery within 6-24 h of onset)and study group(n=40,surgery within 6 h of onset).The clinical efficacy,serum indexes,hemodynamic indexes,brain metabolism indexes,neurological function and self-care ability of the two groups were compared.Results The total effective rate of treatment in the study group was significantly higher than that in the control group(P<0.05).After treatment,the levels of vascular endothelial growth factor(VEGF),angiopoietin-1(Ang-1)and vasopressin(AVP)in the study group were significantly lower than those in the control group,and the level of fetal liver kinase-1(FLK-1)was significantly higher than that in the control group(P<0.05).After treatment,the peak systolic velocity(PSV),mean velocity(Vm),N-acetylaspartate(NAA)/creatine(Cr)in the study group were significantly higher than those in the control group,and choline(Cho)/Cr was significantly lower than that in the control group(P<0.05).After treatment,the score of the National Institutes of Health Stroke Scale(NIHSS)in the study group was significantly lower than that of the control group,and the Modified Barthel Index(MBI)score was significantly higher than that of the control group(P<0.05).Conclusion Ultra-early small bone window minimally invasive cerebral hemorrhage removal is effective in the treatment of cerebral hemorrhage,it can improve serum indexes,brain circulation and metabolism,and promote the recovery of neurological function and self-care ability of patients.

cerebral hemorrhagesmall bone window minimally invasive cerebral hemorrhage removaltreatment opportunityself-care ability

赵金龙、李智斌、刘涛、高立贵

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澄城县医院神经外科,陕西渭南,715200

陕西省森林工业职工医院神经外科,陕西西安,710300

西安交通大学第二附属医院神经外科,陕西西安,710000

脑出血 小骨窗微创脑出血清除术 治疗时机 生活自理能力

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(19)