摘要
目的 探讨老年下肢水肿患者合并肌间静脉血栓(CMVT)形成的危险因素.方法 收集2020年1月至2021年10月我院收治的101例老年下肢水肿患者的临床资料,根据是否发生CMVT将其分为血栓组和非血栓组.采用多因素Logistic回归分析影响老年下肢水肿患者发生CMVT的危险因素.结果 101例老年下肢水肿患者中,48例发生CMVT,53例未发生CMVT.单因素分析结果显示,两组的合并糖尿病占比、白蛋白、低密度脂蛋白(LDL)、D-二聚体(D-D)、N-末端B型脑钠肽前体(NT-proBNP)水平、日常生活活动能力量表(ADL)、Caprini分级及卧床、服用抗凝药物情况比较,差异具有统计学意义(P＜0.05).多因素Logistic回归分析结果显示,合并糖尿病、LDL、D-D、NT-proBNP、ADL、Caprini分级、卧床是影响老年下肢水肿患者发生CMVT的危险因素,服用抗凝药物是保护因素(P＜0.05).结论 合并糖尿病、LDL、D-D、NT-proBNP水平升高、ADL重度、Caprini分级高危及以上及卧床是老年下肢水肿患者发生CMVT的危险因素,早期进行危险因素的筛查及诊治,对减少CMVT的发生具有重要意义.
Abstract
Objective To explore the risk factors of calf muscle vein thrombosis(CMVT)in elderly patients with lower extremity edema.Methods The clinical data of 101 elderly patients with lower extremity edema admitted in our hospital from January 2020 to October 2021 were collected.According to whether CMVT occurred,the patients were divided into thrombus group and non-thrombus group.Multiple Logistic regression analysis was used to analyze the risk factors of CMVT in elderly patients with lower extremity edema.Results Among 101 elderly patients with lower extremity edema,48 patients had CMVT and 53 patients had no CMVT.The results of univariate analysis showed that there were statistically significant differences in the proportion of diabetes mellitus,albumin,low-density lipoprotein(LDL),D-dimer(D-D),N-terminal pro-B-type natriuretic peptide(NT-proBNP)levels,Activities of Daily Living(ADL),Caprini grade,bed rest and anticoagulant medication between the two groups(P＜0.05).Multiple Logistic regression analysis results showed that diabetes mellitus,LDL,D-D,NT-proBNP,ADL,Caprini classification and bed rest were risk factors for CMVT in elderly patients with lower extremity edema,and anticoagulant medication was a protective factor(P＜0.05).Conclusion Diabetes mellitus,elevated levels of LDL,D-D and NT-proBNP,severe ADL,high risk above of Caprini and bed rest are risk factors for CMVT in elderly patients with lower extremity edema.Early screening and diagnosis and treatment of risk factors are of great significance to reduce the occurrence of CMVT.
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