Effect of modified Chaigui Wendan decoction on insomnia of liver stagnation phlegm type and its influences on sleep quality and hyperarousal state
Objective To explore the effect of modified Chaigui Wendan decoction on insomnia of liver stagnation phlegm type and its influences on sleep quality and hyperarousal state.Methods A total of 200 patients with insomnia of liver stagnation phlegm type admitted from January 2019 to January 2023 were selected as the research objects.According to the random number table method,the patients were divided into control group(100 cases,treated with eszopiclone)and observation group(100 cases,treated with modified Chaigui Wendan decoction on the basis of the control group).The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group(P＜0.05).After treatment,the scores of Pittsburgh Sleep Quality Index(PSQI)and Hyperarousal Scale(HAS)in the observation group were lower than those in the control group(P＜0.05).After treatment,the levels of melatonin(MT)and dopamine(DA)in the observation group were higher than those in the control group(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion The modified Chaigui Wendan decoction in the treatment of insomnia patients with liver stagnation phlegm type has a satisfactory effect.It can enhance sleep quality,improve hyperarousal state,promote the secretion of MT and DA,and will not increase the risk of adverse reactions.
Chaigui Wendan decoctioninsomnialiver stagnation phlegm typesleep qualityhyperarousal state
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