高膳食纤维干预对肥胖症伴糖耐量异常患者内脏脂肪和胰岛内分泌系统的影响

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中文摘要：目的分析高膳食纤维干预对肥胖症伴糖耐量异常患者内脏脂肪和胰岛内分泌系统的影响。方法选取2021年5月至2023年5月就诊于陕西省中医医院的60例肥胖症伴糖耐量异常患者为研究对象，依据随机数字表法将其分为对照组和观察组，每组 30 例。对照组接受限制能量平衡膳食(CRD)干预，观察组在此基础上实施高膳食纤维干预。比较两组的干预效果。结果观察组的治疗总有效率高于对照组(P<0。05)。干预后，两组的脂肪量、体脂率(BFP)均降低，且观察组低于对照组(P<0。05)。干预后，两组的空腹血清胰岛素(FINS)、稳态模型评估的胰岛素抵抗指数(HOMA-IR)、瘦素水平均降低，且观察组低于对照组(P<0。05)。干预后，两组的内脏脂肪指数(VFI)、腹腔脂肪厚度、肝前脂肪厚度、心外膜脂肪厚度均降低，且观察组低于对照组(P<0。05)。观察组的满意度明显高于对照组(P<0。05)。结论高膳食纤维干预可显著减少肥胖症伴糖耐量异常患者的脂肪蓄积，改善其胰岛内分泌系统功能，提高治疗满意度。

外文标题：Effects of high dietary fiber intervention on visceral fat and pancreatic islet endocrine system in obesity patients with abnormal glucose tolerance

外文摘要：Objective To analyze the effects of high dietary fiber intervention on visceral fat and pancreatic islet endocrine system in obesity patients with abnormal glucose tolerance.Methods From May 2021 to May 2023,60 obesity patients with abnormal glucose tolerance who were treated in Shaanxi Provincial Hospital of Chinese Medicine were selected as the research objects.According to the random number table method,the patients were divided into control group and observation group,with 30 cases in each group.The control group received calorie restrict diet(CRD)intervention,and the observation group implemented high dietary fiber intervention on this basis.The intervention effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).After intervention,the fat mass and body fat percentage(BFP)of the two groups decreased,and those in the observation group were lower than the control group(P<0.05).After intervention,the levels of fasting serum insulin(FINS),homeostasis model assessment insulin-resistance index(HOMA-IR)and leptin in the two groups decreased,and those in the observation group were lower than the control group(P<0.05).After intervention,the viscera fat index(VFI),abdominal fat thickness,prehepatic fat thickness and epicardial fat thickness of the two groups decreased,and those in the observation group were lower than the control group(P<0.05).The satisfaction of the observation group was significantly higher than that of the control group(P<0.05).Conclusion High dietary fiber intervention can significantly reduce fat accumulation in obesity patients with abnormal glucose tolerance,ameliorate pancreatic islet endocrine system function,and improve treatment satisfaction.

外文关键词：

high dietary fiberobesityabnormal glucose tolerancevisceral fatpancreatic islet endocrine system

作者：

尹薇、袁捷、姚珍珍、于鹏龙

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作者单位：

陕西省中医医院,陕西西安,710000

重庆三峡医药高等专科学校,重庆,404120

关键词：

高膳食纤维肥胖症糖耐量异常内脏脂肪胰岛内分泌系统

基金：

陕西省卫生健康科研基金项目重庆市教育委员会科学技术研究项目

项目编号：

2021E012KJQN202102713

出版年：

2024

DOI：

10.19347/j.cnki.2096-1413.202421005

临床医学研究与实践

ISSN：

年,卷(期)：2024.9(21)