首页|甲状腺全切除术对甲状腺癌患者术后并发症及复发率的影响

甲状腺全切除术对甲状腺癌患者术后并发症及复发率的影响

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目的 分析甲状腺全切除术对甲状腺癌患者术后并发症及复发率的影响。方法 将我院2020 年1 月至2022年11月收治的70 例甲状腺癌患者纳入本次研究,所有患者均予以甲状腺全切除术治疗。统计患者的手术疗效、手术指标、术后并发症发生情况、复发率、甲状腺功能指标及生化指标。结果 患者的治疗总有效率为97。14%(68/70);患者的平均手术时长、术中出血量、住院时长分别为(91。01±10。12)min、(235。24±32。17)mL、(17。14±2。42)d;并发症总发生率为7。14%;1年内的复发率为1。43%(1/70)。术后,患者的促甲状腺激素(TSH)、三碘甲状原氨酸(T3)、四碘甲状腺原氨酸(T4)、甲状腺过氧化物酶抗体(TPOAb)、25-羟维生素D(25-OHD)、癌胚抗原(CEA)及鳞状细胞癌抗原(SCC)水平显著低于术前,游离三碘甲状腺原氨酸(FT3)、游离四碘甲状腺原氨酸(FT4)水平显著高于术前(P<0。05)。结论 甲状腺癌患者行甲状腺全切除术治疗具有较高病灶切除率,且复发率较低,但对喉返神经损伤较大,术后并发症较高,在临床应用中可根据患者具体情况选择。
Effects of total thyroidectomy on postoperative complications and recurrence rate in patients with thyroid cancer
Objective To analyze the effects of total thyroidectomy on postoperative complications and recurrence rate in patients with thyroid cancer.Methods A total of 70 patients with thyroid cancer admitted in our hospital from January 2020 to November 2022 were included in this study.All patients were treated with total thyroidectomy.The surgical efficacy,surgical indicators,postoperative complications,recurrence rate,thyroid function indicators and biochemical indicators of the patients were counted.Results The total effective rate was 97.14%(68/70).The average operation time,intraoperative blood loss and hospitalization time of the patients were(91.01±10.12)min,(235.24±32.17)mL and(17.14±2.42)d,respectively.The total incidence of complications was 7.14%.The recurrence rate within 1 year was 1.43%(1/70).After operation,the levels of thyroid-stimulating hormone(TSH),triiodothyronine(T3),tetraiodothyronine(T4),thyroid peroxidase antibody(TPOAb),25-hydroxyvitamin D(25-OHD),carcinoembryonic antigen(CEA)and squamous cell carcinoma antigen(SCC)were significantly lower than those before operation,and the levels of free triiodothyronine(FT3)and free tetraiodothyronine(FT4)were significantly higher than those before operation(P<0.05).Conclusion Total thyroidectomy for patients with thyroid cancer has a higher lesion resection rate and a lower recurrence rate,but it has a greater injury to the recurrent laryngeal nerve and higher postoperative complications.It can be selected according to the specific conditions of patients in clinical application.

thyroid cancerhemithyroidectomytotal thyroidectomyrecurrent laryngeal nerve

陈智全、计美妮、李昊

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阿克苏地区第一人民医院,新疆 阿克苏,843000

甲状腺癌 甲状腺半切除术 甲状腺全切除术 喉返神经

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(21)