首页|宣白清肺解毒汤联合西药治疗社区获得性肺炎(痰热壅肺证)临床研究

宣白清肺解毒汤联合西药治疗社区获得性肺炎(痰热壅肺证)临床研究

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目的 研究宣白清肺解毒汤联合西药治疗社区获得性肺炎(CAP)(痰热壅肺证)的效果。方法 选取2021年2 月至 2023 年 2 月收治的 120 例CAP(痰热壅肺证)患者作为研究对象,以随机数字表法将其分为西药组和联合组,各60例。西药组采用西药治疗,联合组在西药组的基础上增加宣白清肺解毒汤治疗。比较两组的临床疗效、中医证候积分、症状消失时间、限定日剂量(DDD)值、住院时间、住院费用以及血清炎症因子水平。结果 联合组的治疗总有效率为95。00%,显著高于西药组的80。00%(P<0。05)。治疗后,联合组的发热、咳嗽、痰壅、气促以及心悸积分均低于西药组(P<0。05)。联合组的退热时间、咳嗽/咯痰消失时间、肺部啰音消失时间及住院时间均短于西药组,DDD值低于西药组,住院费用少于西药组(P<0。05)。治疗后,联合组的白细胞介素-6(IL-6)、降钙素原(PCT)及C-反应蛋白(CRP)水平均低于西药组(P<0。05)。结论 宣白清肺解毒汤联合西药治疗CAP(痰热壅肺证)的效果较为理想,可减轻肺部炎症反应程度。
Clinical study on Xuanbai Qingfei Jiedu decoction combined with western medicine in the treatment of community acquired pneumonia(phlegm-heat obstructing lung syndrome)
Objective To study the effect of Xuanbai Qingfei Jiedu decoction combined with western medicine in the treatment of community acquired pneumonia(CAP)(phlegm-heat obstructing lung syndrome).Methods A total of 120 patients with CAP(phlegm-heat obstructing lung syndrom)admitted from February 2021 to February 2023 were selected as the research objects,and the patients were divided into western medicine group and combined group by random number table method,with 60 cases in each group.The western medicine group was treated with western medicine,and the combined group was treated with Xuanbai Qingfei Jiedu decoction on the basis of the western medicine group.The clinical efficacy,TCM syndrome scores,symptom disappearance time,defined daily dose(DDD)value,hospitalization time,hospitalization expenses,and serum inflammatory factors levels were compared between the two groups.Results The total effective rate of treatment in the combined group was 95.00%,which was significantly higher than 80.00%in the western medicine group(P<0.05).After treatment,the scores of fever,cough,phlegm obstruction,shortness of breath and palpitation in the combined group were lower than those in the western medicine group(P<0.05).The antipyretic time,cough/expectoration disappearance time,lung rale disappearance time and hospitalization time of the combined group were shorter than those of the western medicine group,the DDD value was lower than that of the western medicine group,and the hospitalization expenses was less than that of the western medicine group(P<0.05).After treatment,the levels of interleukin-6(IL-6),procalcitonin(PCT)and C-reactive protein(CRP)in the combined group were lower than those in the western medicine group(P<0.05).Conclusion The Xuanbai Qingfei Jiedu decoction combined with western medicine in the treatment of CAP(phlegm-heat obstructing lung syndrome)has ideal effect,which can reduce the degree of lung inflammation.

community acquired pneumoniaphlegm-heat obstructing lung syndromeXuanbai Qingfei Jiedu decoctioninflammatory factor

毛娅

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安康市中医医院呼吸科,陕西 安康,725000

社区获得性肺炎 痰热壅肺证 宣白清肺解毒汤 炎症因子

陕西省中医药管理局委托项目

2021-ZZ-LC019

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(21)