首页|益肺养阴平喘汤联合布地奈德治疗小儿支气管哮喘的临床效果及对预后的影响

益肺养阴平喘汤联合布地奈德治疗小儿支气管哮喘的临床效果及对预后的影响

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目的 分析益肺养阴平喘汤联合布地奈德治疗小儿支气管哮喘(BA)的临床效果。方法 选取2020年 1月至 2022 年 12 月扶风县中医医院儿科收治的 86 例BA患儿为研究对象,以治疗措施不同将其分为西药组(43例,布地奈德)和中西结合组(43例,益肺养阴平喘汤联合布地奈德)。比较两组的治疗效果。结果 中西结合组的治疗总有效率高于西药组,差异具有统计学意义(P<0。05)。治疗后,中西结合组的白三烯B4(LTB4)、白细胞介素-2(IL-2)、肿瘤坏死因子-α(TNF-α)、C-反应蛋白(CRP)水平低于西药组,差异具有统计学意义(P<0。05)。治疗后,中西结合组的每千克体重潮气量(VT/kg)、呼吸频率(RR)、呼气流量峰值(PEF)、达峰时间比(TPTEF/TE)、最大肺活量(VCmax)、最大通气量(MVV)优于西药组,差异具有统计学意义(P<0。05)。中西结合组的不良反应总发生率低于西药组,差异具有统计学意义(P<0。05)。结论 益肺养阴平喘汤联合布地奈德治疗BA患儿可取得安全高效的理想效果,值得临床推广和应用。
Clinical effect of Yifei Yangyin Pingchuan decoction combined with budesonide in the treatment of bronchial asthma in children and its influence on prognosis
Objective To analyze the clinical effect of Yifei Yangyin Pingchuan decoction combined with budesonide in the treatment of bronchial asthma(BA)in children.Methods A total of 86 children with BA admitted in the pediatrics department of Traditional Chinese Medicine Hospital of Fufeng from January 2020 to December 2022 were selected as the research objects.The children were divided into western medicine group(43 cases,budesonide)and Chinese-western combination group(43 cases,Yifei Yangyin Pingchuan decoction combined with budesonide)according to different treatment measures.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the Chinese-western combination group was higher than that in the western medicine group,and the difference was statistically significant(P<0.05).After treatment,the levels of leukotriene B4(LTB4),interleukin-2(IL-2),tumor necrosis factor-α(TNF-α)and C-reactive protein(CRP)in the Chinese-western combination group were lower than those in the western medicine group,and the differences were statistically significant(P<0.05).After treatment,the tidal volume per kilogram(VT/kg),respiratory rate(RR),peak expiratory flow(PEF),ratio of the time to reach peak tidal expiratory flow to total expiratory time(TPTEF/TE),maximum vital capacity(VCmax)and maximal voluntary ventilation(MVV)in the Chinese-western combination group were better than those in the western medicine group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the Chinese-western combination group was lower than that in the western medicine group,and the difference was statistically significant(P<0.05).Conclusion Yifei Yangyin Pingchuan decoction combined with budesonide in the treatment of BA children can achieve safe and efficient ideal results,which is worthy of clinical promotion and application.

bronchial asthmabudesonideYifei Yangyin Pingchuan decoction

汤满青、张智军

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西安市长安区中医医院药剂科,陕西 西安,710100

扶风县中医医院儿科,陕西 宝鸡,722200

支气管哮喘 布地奈德 益肺养阴平喘汤

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(21)