摘要
随着生活节奏的加快、工作压力的增加,慢性疲劳综合征(CFS)发病日益增多,然而其病因和发病机制尚未明确.近年来,大量研究表明本病可能与病毒感染、生物遗传、社会心理等因素相关,并成为国内外研究者关注的热点.目前临床治疗CFS主要强调的是消除诱因、缓解症状,因此掌握该疾病的流行病学特点、明确其病因与病机尤为重要.本文就CFS的发病因素展开阐述,围绕神经内分泌改变、免疫系统紊乱、蛋白质异常对该病病机进行探讨,以期为CFS的诊治、预防提供新方向.
Abstract
With the acceleration of life rhythm and the increase of work pressure,the incidence of chronic fatigue syndrome(CFS)is increasing,but its etiology and pathogenesis are not yet clear.In recent years,a large number of studies have shown that this disease may be related to viral infection,biological genetics,social psychology and other factors,and has become a hot topic for researchers at home and abroad.At present,the clinical treatment of CFS mainly emphasizes the elimination of incentives and relief of symptoms.Therefore,it is particularly important to grasp the epidemiological characteristics of the disease and clarify its etiology and pathogenesis.In this paper,the pathogenic factors of CFS are expounded,and the pathogenesis of the disease is discussed around neuroendocrine changes,immune system disorders and protein abnormalities,in order to provide a new direction for the diagnosis,treatment and prevention of CFS.
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