Effect of acupuncture combined with Qingre Anshen decoction on insomnia of phlegm-heat disturbing heart type and its influences on neurotransmitter levels
Objective To explore the effect of acupuncture combined with Qingre Anshen decoction on insomnia of phlegm-heat disturbing heart type and its influences on neurotransmitter levels.Methods A total of 90 patients with phlegm-heat disturbing heart type insomnia admitted from January 2020 to January 2023 were selected as the research objects,and the patients were divided into control group and observation group by random number table method,with 45 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with acupuncture and Qingre Anshen decoction on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was significantly higher than that in the control group(P＜0.05).After treatment,the Pittsburgh Sleep Quality Index(PSQI)score of the observation group was lower than that of the control group,and the 36-item Short Form Health Survey(SF-36)score was higher than that of the control group(P＜0.05).After treatment,the levels of 5-hydroxytryptamine(5-HT),dopamine(DA),glial cell line derived neurotrophic factor(GDNF)and brain-derived neurotrophic factor(BDNF)in the observation group were significantly higher than those in the control group(P＜0.05).Conclusion The acupuncture combined with Qingre Anshen decoction in the treatment of insomnia of phlegm-heat disturbing heart type has satisfactory effect,it can improve the sleep quality and quality of life of patients,and can also regulate the expression of neurotransmitters such as 5-HT,DA,GDNF and BDNF,which is worthy of promotion and application.
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