首页|成年近视患者眼轴长度与眼部生物学特征的相关性研究

成年近视患者眼轴长度与眼部生物学特征的相关性研究

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目的 对比不同眼轴长度(AL)成年近视患者的眼部生物学测量结果,探讨AL与其他眼部生物学参数之间的相关性。方法 收集2021 年1月至12月在我院就诊的413例(826 眼)成年近视患者的病例资料,根据AL分为四组:A组(102 眼)AL<24 mm,B组(181 眼)AL 24~<25 mm,C组(288 眼)AL 25~<26 mm,D组(255眼)AL≥26 mm。测量所有患者的AL、平均角膜曲率(Km)、角膜曲率半径(CR)、前房深度(ACD)、中央角膜厚度(CCT),计算AL/CR。比较不同AL近视患者眼部生物学测量结果的差异;并采用Pearson相关或Spearman秩相关分析AL与其他眼部生物学参数的相关性。结果 四组患者的Km、AL/CR、ACD、SE及CCT比较,差异具有统计学意义(P<0。001)。Pearson相关性分析结果显示,AL与AL/CR、ACD呈正相关(r=0。607、0。359,P<0。001);AL与Km呈负相关(r=-0。658,P<0。001)。Spearman相关分析结果显示,AL与SE呈负相关(r=-0。656,P<0。001);AL与CCT呈正相关(r=0。145,P<0。001)。结论 AL与近视患者眼部生物学参数相关,随着AL的增长,Km降低,AL/CR增加,ACD变深,SE降低,CCT增厚。
Correlation between axial length and ocular biological characteristics in adult myopic patients
Objective To compare the ocular biological measurements of adult myopic patients with different axial lengths(AL)and explore the correlation between AL and other ocular biological parameters.Methods The clinical data of 413 adult myopic patients(826 eyes)who were treated in our hospital from January to December 2021 were collected.According to AL,the patients were divided into four groups:group A(102 eyes)AL<24 mm,group B(181 eyes)AL 24-<25 mm,group C(288 eyes)AL 25-<26 mm and group D(255 eyes)AL≥26 mm.AL,mean keratometry(Km),corneal radius(CR),anterior chamber depth(ACD)and central corneal thickness(CCT)were measured in all patients,and AL/CR was calculated.The differences of ocular biological measurements in myopic patients with different AL were compared;Pearson correlation or Spearman rank correlation was used to analyze the correlation between AL and other ocular biological parameters.Results There were significant differences in Km,AL/CR,ACD,SE and CCT among the four groups(P<0.001).Pearson correlation analysis showed that AL was positively correlated with AL/CR and ACD(r=0.607,0.359,P<0.001);AL was negatively correlated with Km(r=-0.658,P<0.001).Spearman correlation analysis showed that AL was negatively correlated with SE(r=-0.656,P<0.001);AL was positively correlated with CCT(r=0.145,P<0.001).Conclusion AL is associated with ocular biological parameters in myopic patients.With the increase of AL,Km decreased,AL/CR increased,ACD deepened,SE reduced,and CCT thickened.

myopiaaxial lengthaxial length-to-corneal rodiusocular biological parameter

钱会、薛劲松、纪玉珂、蒋沁、陈楠

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南京医科大学附属眼科医院,江苏 南京,210029

近视 眼轴长度 眼轴长度与角膜曲率半径比值 眼部生物学参数

江苏省医院协会江苏现代医院管理研究中心2021年度医院管理创新研究课题

JSYGY-2-2021-467

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(23)