Correlation between axial length and ocular biological characteristics in adult myopic patients
Objective To compare the ocular biological measurements of adult myopic patients with different axial lengths(AL)and explore the correlation between AL and other ocular biological parameters.Methods The clinical data of 413 adult myopic patients(826 eyes)who were treated in our hospital from January to December 2021 were collected.According to AL,the patients were divided into four groups:group A(102 eyes)AL<24 mm,group B(181 eyes)AL 24-<25 mm,group C(288 eyes)AL 25-<26 mm and group D(255 eyes)AL≥26 mm.AL,mean keratometry(Km),corneal radius(CR),anterior chamber depth(ACD)and central corneal thickness(CCT)were measured in all patients,and AL/CR was calculated.The differences of ocular biological measurements in myopic patients with different AL were compared;Pearson correlation or Spearman rank correlation was used to analyze the correlation between AL and other ocular biological parameters.Results There were significant differences in Km,AL/CR,ACD,SE and CCT among the four groups(P<0.001).Pearson correlation analysis showed that AL was positively correlated with AL/CR and ACD(r=0.607,0.359,P<0.001);AL was negatively correlated with Km(r=-0.658,P<0.001).Spearman correlation analysis showed that AL was negatively correlated with SE(r=-0.656,P<0.001);AL was positively correlated with CCT(r=0.145,P<0.001).Conclusion AL is associated with ocular biological parameters in myopic patients.With the increase of AL,Km decreased,AL/CR increased,ACD deepened,SE reduced,and CCT thickened.