Multidimensional analysis of core prescriptions of listed Chinese patent medicines for postpartum hypogalactia
Objective To analyze the prescription rules,core prescriptions and mechanism of action of listed Chinese patent medicines for postpartum hypogalactia.Methods The Chinese patent medicines for the treatment of postpartum hypogalactia were collected from the Chinese patent medicine value evaluation information database,and the frequency statistics and association rules were used to analyze the medication characteristics and prescription rules.By using the network module division method,the core prescriptions were excavated,and the mechanism of action was analyzed from the perspective of component-target-biological pathway.Results A total of 23 kinds of Chinese patent medicine prescriptions were collected,including 69 kinds of traditional Chinese medicine,involving 8 dosage forms and 2 drug categories.The most frequently used drugs are Angelicae Sinensis Radix and Vaccariae Semen,while the most supported drug pairs was Vaccariae Semen-Angelicae Sinensis Radix.The core components of the prescriptions were Vaccariae Semen,Chuanxiong Rhizoma,Angelicae Sinensis Radix,Paeoniae Radix Alba and Glycyrrhizae Radix et Rhizoma,all could regulate prolactin and its downstream signaling pathway.Conclusion The combination of association rules and network module division can analyze the medication rules of postpartum hypogalactia in multiple dimensions,and provide references for the clinical application of traditional Chinese medicine in the treatment of postpartum hypogalactia.
NETL
NSTL
万方数据
