Analysis of etiology and clinical characteristics of thyrotoxicosis in children
Objective To analyze the etiology and clinical characteristics of thyrotoxicosis in children.Methods Sixty-five children with thyrotoxicosis who were treated in our hospital from January 2016 to March 2022 were selected and divided into Graves'disease(GD)children and non-GD children according to the etiology.The medical history data of the children were collected and the clinical characteristics of the disease were analyzed.Results Among the 65 children with thyrotoxicosis,57 cases(87.69%)were GD and 8 cases(12.31%)were non-GD.There were statistically significant differences in the age,proportion of puberty,male,fever,thyroid pain,thyroid stimulating hormone(TSH),free thyroxine(FT4),free triiodothyronine(FT3),tetraiodothyronine(T4),triiodothyronine(T3),positive thyrotrophin receptor antibody(TRAb),diffuse goiter enlargement and increased high-sensitive C-reactive protein(hs-CRP)between GD and non-GD children(P<0.05).Conclusion The etiology of thyrotoxicosis in children is complex,and some clinical features have certain value for the differential diagnosis of GD and non-GD.
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