Value of combined detection of PT,PLT and AFP in the diagnosis of cirrhosis
Objective To analyze the value of combined detection of prothrombin time(PT),platelet count(PLT)and alpha-fetoprotein(AFP)in the diagnosis of cirrhosis.Methods A total of 100 patients with suspected cirrhosis admitted from February 2020 to February 2022 were selected as observation group,and 100 volunteers who went to the hospital for health examination during the same period were randomly selected as healthy group.All subjects were tested for PT,PLT and AFP,and the diagnostic efficacy of single and combined detection of the three for cirrhosis was analyzed.Results The PT in the observation group was longer than that in the healthy group,the PLT was lower than that in the healthy group,the AFP level was higher than that in the healthy group,and the differences were statistically significant(P<0.05).In the observation group,the PT of patients with Child-Pugh grade A was shorter than that of patients with grade B and C,the PLT was higher than that of patients with grade B and C,the AFP level was lower than that of patients with grade B and C,and the differences were statistically significant(P<0.05);the PT of patients with Child-Pugh grade B was shorter than that of patients with grade C,the PLT was higher than that of patients with grade C,the AFP level was lower than that of patients with grade C,and the differences were statistically significant(P<0.05).There were no significant differences in the sensitivity,specificity and accuracy of PT,PLT and AFP in the single diagnosis of cirrhosis(P>0.05);there was no significant difference in the sensitivity of combined and single detection of PT,PLT and AFP in the diagnosis of cirrhosis(P>0.05);the specificity and accuracy of combined detection of PT,PLT and AFP in the diagnosis of cirrhosis were significantly higher than those of single diagnosis,and the differences were statistically significant(P<0.05).Conclusion The combined detection of PT,PLT and AFP has high diagnostic value for cirrhosis.
NETL
NSTL
万方数据
