Effect of intrauterine balloon tamponade combined with carboprost tromethamine-misoprostol in the treatment of postpartum hemorrhage caused by uterine inertia after cesarean section and its influences on uterine hemodynamic indexes
Objective To explore the effect of intrauterine balloon tamponade combined with carboprost tromethamine-misoprostol in the treatment of postpartum hemorrhage caused by uterine inertia after cesarean section.Methods A total of 80 patients with postpartum hemorrhage caused by uterine inertia after cesarean section admitted from February 2020 to March 2023 were selected as the research objects,and the patients were divided into control group and observation group by random number table method,with 40 cases in each group.The control group was treated with carboprost tromethamine-misoprostol,and the observation group was treated with intrauterine balloon tamponade on the basis of the control group.The therapeutic effect related indexes,uterine hemodynamics indexes and coagulation function indexes of the two groups were compared.Results The success rate of hemostasis in the observation group was higher than that in the control group,the incidence of incomplete uterine involution and the rate of rebleeding were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the end diastolic velocity(EDV)and peak systolic velocity(PSV)of uterine artery in the observation group were higher than those in the control group,the resistance index(RI)and pulsatility index(PI)were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the level of fibrinogen(Fib)in the observation group was higher than that in the control group,the prothrombin time(PT),activated partial thromboplastin time(APTT)and thrombin time(TT)were shorter than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The intrauterine balloon tamponade combined with carboprost tromethamine-misoprostol in the treatment of patients with postpartum hemorrhage caused by uterine inertia after cesarean section can improve the body's coagulation function,regulate uterine hemodynamic indexes,improve the overall efficacy,which is worthy of promotion and application in chinical practice.
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