Study on the correlation between BMI and clinical characteristics and molecular typing of breast cancer in women in southern Xinjiang
Objective To explore the correlation between body mass index(BMI)and clinical characteristics and molecular typing of breast cancer in women in southern Xinjiang.Methods A total of 165 female breast cancer patients who were treated in the General Hospital of the Third Division of Xinjiang Production and Construction Corps from January 2020 to December 2022 were retrospectively selected as the research objects.According to the BMI at the time of hospitalization,the patients were divided into lean group(BMI<18.5 kg/m2),normal group(BMI 18.5-23.9 kg/m2),overweight group(BMI 24.0-27.9 kg/m2),and obese group(BMI≥28 kg/m2).The general data,pathological features and main molecular typing of the four groups were compared.Results There were statistically significant differences in hyperlipidemia and menopausal status among the four groups(P<0.05).There was statistically significant difference in lymph node metastasis among the four groups(P<0.05).There was statistically significant difference in the proportion of positive human epidermal growth factor receptor-2(HER-2)among the four groups(P<0.05).Conclusion BMI of women in southern Xinjiang is associated with hyperlipidemia,menopausal status,lymphatic metastasis and HER-2 positive in breast cancer patients.
southern Xinjiangbreast cancerbody mass indexlymphatic metastasismolecular typing
万方数据
维普
