Effect of Honghe Fujie lotion combined with nifuratel nysfungin vaginal soft capsules and Lacidophilin vaginal capsules sequential medication in the treatment of mycotic vaginitis and its influences on vaginal microecology,PCT and CRP levels
Objective To investigate the effect of Honghe Fujie lotion combined with nifuratel nysfungin vaginal soft capsules and Lacidophilin vaginal capsules sequential medication in the treatment of mycotic vaginitis.Methods A total of 100 patients with mycotic vaginitis admitted from January 2021 to October 2022 were selected and divided into control group and observation group according to the random number table method,with 50 cases in each group.The control group was treated with sequential medication of nifuratel nysfungin vaginal soft capsules and Lacidophilin vaginal capsules.The observation group was treated with Honghe Fujie lotion on the basis of the control group.The therapeutic effects of the two groups were compared.Results After treatment,the scores of vulva pruritus,leucorrhea abnormality and vulva swelling in the observation group were significantly lower than those in the control group(P<0.05).After treatment,the content of Lactic acid bacteria in the observation group was higher than that in the control group,and the content of Bacteroides and Candida albicans were lower than those in the control group(P<0.05).After treatment,the levels of C-reactive protein(CRP)and procalcitonin(PCT)in the observation group were lower than those in the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05);the recurrence rate of the observation group was significantly lower than that of the control group(P<0.05).Conclusion Honghe Fujie lotion combined with nifuratel nysfungin vaginal soft capsules and Lacidophilin vaginal capsules sequential medication in the treatment of patients with mycotic vaginitis has satisfactory effect.It can quickly control clinical symptoms,regulate vaginal microecology,reduce CRP,PCT levels and recurrence rate,and has high safety.
万方数据
维普
