Effects of vitamin D deficiency on the onset and control of asthma in children
Objective To study the effects of vitamin D deficiency on the onset and control of asthma in children.Methods A total of 141 children with asthma admitted in the First Hospital in Weinan from January 2020 to December 2022 were selected as experimental group,and 140 children who underwent physical examination during the same period were selected as control group.The serum vitamin D levels of the two groups were compared;the levels of serum vitamin D in children with different degrees of asthma were compared;the influencing factors of asthma control level were analyzed.Results The 25-hydroxyvitamin D[25-(OH)D]level of the experimental group was lower than that of the control group,and the proportion of vitamin D deficiency was higher than that of the control group(P<0.05).The proportion of vitamin D deficiency in children with severe asthma was higher than that in children with mild and moderate asthma,and the proportion of vitamin D deficiency in children with moderate asthma was higher than that in children with mild asthma(P<0.05).The proportions of age<6 years old,number of asthma attacks in the past 1 year>2 times,course of disease≥2 years,vitamin D deficiency and dust exposure history in the good asthma control group were lower than those in the poor control group(P<0.05).Multivariate Logistic regression analysis results showed that age<6 years old,number of asthma attacks in the past year>2 times,course of disease≥2 years,vitamin D deficiency and dust exposure history were risk factors for poor asthma control(P<0.05).Conclusion Vitamin D deficiency is closely related to the onset and control of asthma in children,which should be given special attention.
万方数据
维普
