Effects of regulated dual channel digestive tract reconstruction surgery with gastric antrum preservation on tumor marker level and nutritional status in patients with advanced gastric cancer
Objective To investigate the effects of regulated dual channel digestive tract reconstruction surgery with gastric antrum preservation on tumor marker levels and nutritional status in patients with advanced gastric cancer.Methods A total of 100 patients with advanced gastric cancer admitted from January 2020 to January 2023 were selected and randomly divided into control group and observation group,with 50 cases in each group.The control group was treated with total gastrectomy Roux-en-Y anastomosis,and the observation group was treated with regulated dual channel digestive tract reconstruction surgery with gastric antrum preservation.The therapeutic effects of the two groups were compared.Results At 2 weeks after operation,the levels of carcinoembryonic antigen(CEA),carbohydrate antigen 19-9(CA19-9)and carbohydrate antigen 72-4(CA72-4)in the observation group were lower than those in the control group(P＜0.05).At 2 weeks after operation,the levels of prealbumin(PA),albumin(ALB)and serum ferritin(SF)in the observation group were higher than those in the control group(P＜0.05).At 2 weeks after operation,the levels of gastrin(GAS)and cholecystokinin(CCK)in the two groups decreased,but those in the observation group were higher than the control group(P＜0.05).The total incidence of complications in the observation group was lower than that in the control group(P＜0.05).Conclusion Regulated dual channel digestive tract reconstruction surgery with gastric antrum preservation is effective in patients with advanced gastric cancer,which can reduce the tumor markers levels and improve nutritional status.
gastric antrum preservationregulated dual channel digestive tract reconstruction surgerygastric cancer
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