首页|地衣芽孢杆菌活菌胶囊治疗肠易激综合征患者的临床效果

地衣芽孢杆菌活菌胶囊治疗肠易激综合征患者的临床效果

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目的 分析地衣芽孢杆菌活菌胶囊治疗肠易激综合征患者的临床效果.方法 选取我院2020年1月至2022年12月收治的100例肠易激综合征患者为研究对象,将其随机分为常规组(50例,常规治疗)和观察组(50例,常规治疗+地衣芽孢杆菌活菌胶囊治疗).比较两组的治疗效果.结果 观察组的治疗总有效率高于常规组,大便次数、大便性状恢复正常时间短于常规组(P<0.05).治疗后,观察组的双歧杆菌、乳杆菌数量多于常规组,肠杆菌数量少于常规组(P<0.05).治疗后,观察组的C-反应蛋白(CRP)、白细胞介素-6(IL-6)、降钙素原(PCT)、白细胞计数(WBC)、胃泌素(GAS)、胃蛋白酶原Ⅰ(PG Ⅰ)及胃蛋白酶原Ⅱ(PGⅡ)水平低于常规组(P<0.05).两组治疗期间的不良反应总发生率比较,差异无统计学意义(P>0.05).结论 地衣芽孢杆菌活菌胶囊治疗肠易激综合征患者可取得安全、高效的理想效果.
Clinical effect of live Bacillus Licheniformis capsule in the treatment of patients with irritable bowel syndrome
Objective To analyze the clinical effect of live Bacillus Licheniformis capsule in the treatment of patients with irritable bowel syndrome.Methods A total of 100 patients with irritable bowel syndrome admitted in our hospital from January 2020 to December 2022 were selected as the research objects and randomly divided into conventional group(50 cases,routine treatment)and observation group(50 cases,routine treatment+live Bacillus Licheniformis capsule treatment).The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the conventional group,and the recovery time of stool frequency and stool character were shorter than those in the conventional group(P<0.05).After treatment,the numbers of Bifidobacterium and Lactobacillus in the observation group were more than those in the conventional group,and the number of Enterobacter was less than that in the conventional group(P<0.05).After treatment,the levels of C-reactive protein(CRP),interleukin-6(IL-6),procalcitonin(PCT),white blood cell(WBC),gastrin(GAS),pepsinogen Ⅰ(PG Ⅰ)and pepsinogen Ⅱ(PG Ⅱ)in the observation group were lower than those in the conventional group(P<0.05).There was no significant difference in the total incidence of adverse reactions during treatment between the two groups(P>0.05).Conclusion Live Bacillus Licheniformis capsule in the treatment of patients with irritable bowel syndrome can achieve safe and efficient ideal effect.

irritable bowel syndromelive Bacillus Licheniformis capsuleadverse reaction

党雅荣、贺金娥

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陕西省延安市洛川县永乡镇卫生院,陕西延安,727400

延安大学附属医院,陕西延安,716000

肠易激综合征 地衣芽孢杆菌活菌胶囊 不良反应

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(28)