首页|布地奈德+鼻内镜手术治疗鼻窦炎-鼻息肉患者的效果及对术后鼻腔功能的影响

布地奈德+鼻内镜手术治疗鼻窦炎-鼻息肉患者的效果及对术后鼻腔功能的影响

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目的 分析布地奈德+鼻内镜手术治疗鼻窦炎-鼻息肉患者的效果及对术后鼻腔功能的影响.方法 选取2020年1月至2022年12月我院收治的150例鼻窦炎-鼻息肉患者为研究对象,以治疗方案差异将其分为常规组(鼻内镜手术)和观察组(布地奈德+鼻内镜手术),每组75例.比较两组的治疗效果.结果 观察组的治疗总有效率高于常规组,差异具有统计学意义(P<0.05).治疗后,观察组的Lund-Kennedy及嗅觉功能评分低于常规组,鼻腔容积大于常规组,差异具有统计学意义(P<0.05).治疗后,观察组的超敏C反应蛋白(hs-CRP)、总免疫球蛋白E(TIgE)水平及嗜酸性粒细胞百分比(EOS%)低于常规组,差异具有统计学意义(P<0.05).术后12、24 h及出院时,观察组的视觉模拟评分法(VAS)评分低于常规组,差异具有统计学意义(P<0.05).结论 布地奈德+鼻内镜手术治疗鼻窦炎-鼻息肉患者可取得理想的治疗效果.
Effect of budesonide+nasal endoscopic surgery in the treatment of patients with sinusitis-nasal polyps and its influence on postoperative nasal function
Objective To analyze the effect of budesonide+nasal endoscopic surgery in the treatment of patients with sinusitis-nasal polyps and its influence on postoperative nasal function.Methods A total of 150 patients with sinusitis-nasal polyps admitted in our hospital from January 2020 to December 2022 were selected as the research objects.According to the difference of treatment plan,the patients were divided into conventional group(nasal endoscopic surgery)and observation group(budesonide+nasal endoscopic surgery),with 75 cases in each group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the conventional group,and the difference was statistically significant(P<0.05).After treatment,the Lund-Kennedy and olfactory function scores of the observation group were lower than those of the conventional group,the nasal cavity volume was larger than that of the conventional group,and the differences were statistically significant(P<0.05).After treatment,the high sensitivity C-reactive protein(hs-CRP),total immunoglobulin E(TIgE)levels and eosinophilia percentage(EOS%)in the observation group were lower than those in the conventional group,and the differences were statistically significant(P<0.05).At 12,24 h after operation and at discharge,the Visual Analogue Scale(VAS)score of the observation group was lower than that of the conventional group,and the difference was statistically significant(P<0.05).Conclusion Budesonide+nasal endoscopic surgery can achieve ideal therapeutic effect in the treatment of patients with sinusitis-nasal polyps.

budesonidenasal endoscopic surgerysinusitisnasal polyp

丁瑜、高旭栋

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陕西省人民医院耳鼻咽喉头颈外科,陕西西安,710068

布地奈德 鼻内镜手术 鼻窦炎 鼻息肉

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(28)