Effect of rotatable and repeatable soft tissue clamp under digestive endoscopy combined with rabeprazole and hemagglutinin in the treatment of acute upper gastrointestinal bleeding in the elderly and its influences on platelet-related factors
Objective To investigate the effect of rotatable and repeatable soft tissue clamp under digestive endoscopy combined with rabeprazole and hemagglutinin in the treatment of acute upper gastrointestinal bleeding in the elderly and its influences on platelet-related factors.Methods A total of 100 elderly patients with acute upper gastrointestinal bleeding admitted from January 2022 to January 2023 were selected as the research objects.According to the different enrollment time,the patients were divided into control group and observation group,with 50 cases in each group.The control group was treated with rabeprazole and hemagglutinin,while the observation group was treated with rotatable and repeatable soft tissue clamp under digestive endoscopy on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was significantly higher than that in the control group(P<0.05).The success rate of hemostasis in the observation group was higher than that in the control group,and the rebleeding rate was lower than that in the control group(P<0.05).The complete hemostasis time,blood pressure stabilization time and abdominal pain disappearance time in the observation group were shorter than those in the control group,and the gastric tube drainage volume was less than that in the control group(P<0.05).After treatment,the platelet aggregation rate,α-granular membrane protein-140(GMP-140),CD63 and CD62P in the observation group were higher than those in the control group(P<0.05).Conclusion The rotatable and repeatable soft tissue clamp under digestive endoscopy combined with rabeprazole and hemagglutinin in the treatment of acute upper gastrointestinal bleeding in the elderly has a satisfactory effect,it can quickly stop bleeding,improve symptoms,effectively enhance the success rate of hemostasis,reduce the rate of rebleeding,and improve the expression of platelet-related factors.
rotatable and repeatable soft tissue clampdigestive endoscopyrabeprazolehemagglutininelderlyacute upper gastrointestinal bleeding
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