Effects of trioxy autoblood therapy combined with anti-tuberculosis treatment on immune function indexes of patients with active pulmonary tuberculosis
Objective To analyze the effects of trioxy autoblood therapy combined with anti-tuberculosis treatment on immune function indexes in patients with active pulmonary tuberculosis(PTB).Methods A total of 100 patients with active PTB admitted from January to December 2020 were selected as the research objects.The patients were divided into control group and trioxy autoblood group by red blue ball random method,with 50 cases in each group.The control group was given conventional anti-tuberculosis treatment,and the trioxy autoblood group was given trioxy autoblood therapy on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of the trioxy autoblood group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in CD4+,CD8+,CD4+/CD8+,CD56+,CD19+and CD45+between the two groups(P>0.05);after treatment,the CD4+,CD4+/CD8+,CD56+and CD45+in the trioxy autoblood group were significantly higher than those in the control group,and the CD8+and CD19+were significantly lower than those in the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in the levels of tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)and interleukin-34(IL-34)between the two groups(P>0.05);after treatment,the levels of TNF-α,CRP and IL-34 in the trioxy autoblood group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Trioxy autoblood therapy combined with conventional anti-tuberculosis treatment can achieve ideal therapeutic effect in patients with active PTB.
active pulmonary tuberculosisanti-tuberculosis treatmenttrioxy autoblood therapy
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