Effects of transumbilical single-port laparoscopic myomectomy and traditional multiport laparoscopic myomectomy on growth factors levels and ovarian function in patients with uterine fibroids
Objective To compare the effects of transumbilical single-port laparoscopic myomectomy and traditional multiport laparoscopic myomectomy on growth factors levels and ovarian function in patients with uterine fibroids.Methods A total of 88 patients with uterine fibroids admitted from September 2021 to February 2022 were selected as the research objects and divided into control group and observation group by random number table method,with 44 cases in each group.The control group was treated with traditional multiport laparoscopic myomectomy,and the observation group was treated with transumbilical single-port laparoscopic myomectomy.The surgical effects of the two groups were compared.Results At discharge,the levels of tumor supplied group of factors(TSGF),insulin like growth factor-1(IGF-1),vascular endothelial growth factor(VEGF)and transforming growth factor-α(TGF-α)in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).At discharge,the levels of anti-Müllerian hormone(AMH)and estradiol(E2)in the observation group were higher than those in the control group,the levels of follicle-stimulating hormone(FSH)and luteinizing hormone(LH)were lower than those in the control group,and the differences were statistically significant(P<0.05).The total incidence of complications and recurrence rate of uterine fibroids in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Compared with traditional multiport laparoscopic myomectomy,transumbilical single-port laparoscopic myomectomy can effectively decrease the impact on the body's growth factors levels,protect ovarian function,reduce the incidence of postoperative complications and recurrence rate,which is worthy of promotion.
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