Establishment of rat common carotid artery arteriovenous end-to-end anastomosis model with anterior facial vein as graft
Objective To establish a training model of common carotid artery(CCA)anastomosis end-to-end in rats with anterior facial vein as autologous graft.Methods Twenty-four SD rats were selected and randomly divided into two groups for classical end-to-end anastomosis of CCA(n=12)and end-to-end anastomosis of CCA with anterior facial vein as autologous graft(n=12).All anastomosis were performed in a discontinuous manner to establish a CCA arteriovenous end-to-end anastomosis model.Results The diameter of CCA in rats was 1.0-1.2 mm,and the diameter of anterior facial vein was 0.8-1.0 mm.The classic CCA end-to-end anastomosis required about 8-10 needles,and the average anastomosis time was(22.75±1.66)min.In the CCA arteriovenous end-to-end anastomosis group with anterior facial vein as autologous graft,each rat needed 2 end-to-end anastomosis,the total anastomosis time was(49.42±2.47)min,each anastomosis required 8-10 needles and took(24.71±1.65)min.The immediate patency rate of all anastomosis and the patency rate after 30 min were 100％.Conclusion The anterior facial vein is used as an autologous graft for rat CCA arteriovenous microvascular end-to-end anastomosis practice,which can simulate end-to-end anastomosis with mismatched vessel diameter and wall thickness.This model is a supplement to the classic CCA end-to-end anastomosis training model.
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