Application value of noninvasive dynamic monitor of cerebral edema in predicting intracranial pressure after intracerebral hemorrhage in rats
Objective To explore the role of noninvasive dynamic monitor of cerebral edema in predicting intracranial pressure(ICP)after intracerebral hemorrhage(ICH)in rats,and to provide reliable technology and theoretical guidance for clinical non-invasive cerebral edema monitoring.Methods After ICH modeling,male SD rats were given intracerebroventricular invasive ICP monitoring,and the disturbance coefficient(DC)was monitored by BORN-BE-Ⅲ noninvasive dynamic monitor of cerebral edema.The law between DC and the development trend of cerebral edema and the correlation between DC and ICP were analyzed.Results ICP continued to rise from 1 to 3 days after modeling;from 4 to 14 days,ICP continued to decrease.DC decreased gradually from 1 to 3 days after modeling,and reached the lowest point on the third day;DC showed a gradual upward trend from 4 to 14 days;DC gradually returned to the normal range from 10 to 14 days;the amplitude of DC variation from 1 to 3 days was greater than that from 4 to 14 days.DC was negatively correlated with ICP.Conclusion The noninvasive dynamic monitor of cerebral edema can monitor the dynamic changes in cerebral edema after ICH and play an important reference role in ICP prediction;compared to invasive intracranial ICP monitoring technology,it has advantages such as safety,effectiveness,and continuous dynamic bedside monitoring,and is a potential new technology in the field of ICP monitoring.
noninvasive dynamic monitor of cerebral edemaintracerebral hemorrhageintracranial pressurecerebral edema
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