Effects of high-flux and low-flux dialysis on inflammatory factors levels in maintenance hemodialysis patients
Objective To analyze the effects of high-flux and low-flux dialysis on inflammatory factors levels in maintenance hemodialysis patients.Methods A total of 200 patients with maintenance hemodialysis admitted from January 2022 to January 2023 were selected as the research objects and divided into control group(n=100)and observation group(n=100)by random number table method.The control group was treated with low-flux dialysis,and the observation group was treated with high-flux dialysis.The therapeutic effects of the two groups were compared.Results After treatment,the levels of cystatin C(CysC),blood urea nitrogen(BUN)and serum creatinine(Scr)in the observation group were lower than those in the control group(P＜0.05).After treatment,the levels of tumor necrosis factor-α(TNF-α),hypersensitive C-reactive protein(hs-CRP)and interleukin-6(IL-6)in the observation group were lower than those in the control group(P＜0.05).After treatment,the level of superoxide dismutase(SOD)in the observation group was higher than that in the control group,and the level of malondialdehyde(MDA)was lower than that in the control group(P＜0.05).After treatment,the levels of albumin(ALB)and total protein(TP)in the observation group were higher than those in the control group(P＜0.05).The total incidence of complications in the observation group was 3.00％,which was lower than 11.00％in the control group(P＜0.05).Conclusion The high-flux dialysis has a significant effect on maintenance hemodialysis patients,which can improve renal function and nutritional status,regulate inflammatory factors and oxidative stress indicators,and reduce the risk of complications.
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