Comparison of outcomes and short-term prognosis between segmentectomy and lobectomy in the treatment of early NSCLC patients with diameter ≤2 cm
Objective To compare the outcomes and short-term prognosis between segmentectomy and lobectomy in the treatment of early non-small cell lung cancer(NSCLC)patients with diameter ≤2 cm.Methods A total of 90 patients with early NSCLC with diameter ≤2 cm admitted in our hospital from March 2020 to March 2023 were selected as the research objects.According to different surgical schemes,the patients were divided into lung segment group(segmentectomy)and lung lobe group(lobectomy),with 45 cases in each group.The therapeutic effects of the two groups were compared.Results There was no significant difference in the total effective rate of treatment between the two groups(P＞0.05).The operation time of the lung lobe group was shorter than that of the lung segment group,and the intraoperative blood loss and total drainage volume 2 d after operation were lower than those of the lung segment group,and the differences were statistically significant(P＜0.05);the postoperative air leakage time,bed rest time and hospitalization time of the lung lobe group were longer than those of the lung segment group,and the differences were statistically significant(P＜0.05).The total incidence of complications in the lung lobe group was higher than that in the lung segment group,and the difference was statistically significant(P＜0.05).After operation,the metabolic equivalent(METs),maximal voluntary ventilation(MVV),maximum oxygen pulse(VO2max/HR)and maximal oxygen consumption per kg body weight(VO2max/kg)in the lung lobe group were lower than those in the lung segment group,and the differences were statistically significant(P＜0.05).After operation,the forced expiratory volume in one second(FEV1),forced vital capacity(FVC)and FEV1/FVC in the lung lobe group were lower than those in the lung segment group,and the differences were statistically significant(P＜0.05).Conclusion Both segmentectomy and lobectomy can achieve better surgical outcomes in the treatment of early NSCLC patients with diameter ≤2 cm,but the former has a better short-term prognosis,which can effectively shorten the postoperative rehabilitation cycle,reduce postoperative complications and restore lung function.
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