Application of propofol target controlled infusion combined with remifentanil anesthesia in anesthesia of patients with ultra-low rectal cancer
Objective To compare the application effects of propofol target controlled infusion combined with remifentanil anesthesia and combined anesthesia of intravenous and inhalation in anesthesia of patients with ultra-low rectal cancer.Methods A total of 82 patients with ultra-low rectal cancer admitted in our hospital from October 2019 to May 2023 were selected as the research objects.According to the difference of anesthesia,the patients were divided into conventional group(41 cases,combined anesthesia of intravenous and inhalation)and observation group(41 cases,propofol target controlled infusion combined with remifentanil anesthesia).The anesthetic effects of the two groups were compared.Results At the time of entering the room(T0),there were no significant differences in heart rate(HR)and oxygen saturation(SpO2)between the two groups(P＞0.05);during intubation(T1)to extubation(T4),HR in the observation group was significantly lower than that in the conventional group,and SpO2 was significantly higher than that in the conventional group(P＜0.05);the fluctuation range of HR and SpO2 in the observation group were smaller than those in the conventional group.At T0,there were no significant differences in mean artery pressure(MAP),central venous pressure(CVP)and mean pulmonary arterial pressure(MPAP)between the two groups(P＞0.05);at T1-T4,MAP and CVP in the observation group were significantly lower than those in the conventional group,and MPAP was significantly higher than that in the conventional group(P＜0.05);the fluctuation range of MAP,CVP and MPAP during anesthesia in the observation group were smaller than those in the conventional group.The total incidences of intraoperative respiratory and circulatory inhibition and postoperative adverse reactions in the observation group were significantly lower than those in the conventional group(P＜0.05).Conclusion Compared with combined anesthesia of intravenous and inhalation,propofol target-controlled infusion combined with remifentanil anesthesia has a more significant application effect in anesthesia of patients with ultra-low rectal cancer.
ultra-low rectal cancerlaparoscopic surgerypropofoltarget controlled infusionremifentanilcombined anesthesia of intravenous and inhalation
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