Application value of multimodal magnetic resonance combined with serum PSA related parameters in the diagnosis of prostate cancer
Objective To explore the value of multimodal MRI Prostate Imaging Reporting and Data System(PI-RADS)score combined with prostate-specific antigen(PSA)related parameters in the diagnosis of prostate cancer(PCa).Methods The clinical and imaging data of 167 patients who underwent prostate MRI in the imaging department were retrospectively analyzed.According to the pathological results,the patients were divided into PCa group and benign prostatic lesion group.The age,PI-RADS score,prostate-specific antigen density(PSAD),total prostate specific antigen(tPSA),free prostate specific antigen/total prostate specific antigen(fPSA/tPSA)were compared between the two groups;the receiver operating characteristic(ROC)curve was constructed to analyze the diagnostic efficacy of PI-RADS score,PSAD and tPSA alone and in combination for PCa.Results Pathological results showed 95 cases of PCa and 72 cases of benign prostatic lesions.The PI-RADS score,PSAD and tPSA in the PCa group were higher than those in the benign prostatic lesion group,and the differences were statistically significant(P＜0.05).ROC curve results showed that PI-RADS score had better diagnostic efficacy for PCa;PI-RADS score+tPSA+PSAD had the best diagnostic efficacy for PCa,but there was no significant difference compared with PI-RADS score+PSAD(P＞0.05).Conclusion PI-RADS score combined with PSAD and tPSA can further improve the diagnostic efficiency and provide a better basis for the diagnosis and puncture of PCa.
prostate cancerProstate Imaging Reporting and Data System scoreprostate-specific antigenprostate-specific antigen density
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