首页|肠内营养支持对肺癌化疗患者营养状态及免疫功能的影响

肠内营养支持对肺癌化疗患者营养状态及免疫功能的影响

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目的 探讨肠内营养支持对肺癌化疗患者营养状态及免疫功能的影响。方法 选取2020 年10月至2023年8月本院收治的72 例肺癌化疗患者为研究对象,依据干预方式将其分为对照组和观察组,各 36例。对照组给予肠外营养支持,观察组给予肠内营养支持。比较两组的干预效果。结果 干预后,观察组的白蛋白(ALB)、前白蛋白(PA)、转铁蛋白(TF)及总蛋白(TP)水平高于对照组,差异具有统计学意义(P<0。05)。干预后,观察组的CD3+、CD4+及CD4+/CD8+高于对照组,CD8+低于对照组(P<0。05)。干预后,观察组的免疫球蛋白M(IgM)、免疫球蛋白A(IgA)及免疫球蛋白G(IgG)水平高于对照组(P<0。05)。观察组的不良反应总发生率低于对照组(P<0。05)。结论 肠内营养支持不仅可改善肺癌化疗患者的营养状态、免疫功能,还可降低不良反应发生风险。
Effects of enteral nutrition support on nutritional status and immune function in patients with lung cancer chemotherapy
Objective To investigate the effects of enteral nutrition support on nutritional status and immune function in patients with lung cancer chemotherapy.Methods A total of 72 patients with lung cancer chemotherapy admitted in our hospital from October 2020 to August 2023 were selected as the research objects.According to the intervention methods,the patients were divided into control group and observation group,with 36 cases in each group.The control group was given parenteral nutrition support,and the observation group was given enteral nutrition support.The intervention effects of the two groups were compared.Results After intervention,the levels of albumin(ALB),prealbumin(PA),transferrin(TF)and total protein(TP)in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).After intervention,the CD3+,CD4+and CD4+/CD8+in the observation group were higher than those in the control group,and the CD8+was lower than that in the control group(P<0.05).After intervention,the levels of immunoglobulin M(IgM),immunoglobulin A(IgA)and immunoglobulin G(IgG)in the observation group were higher than those in the control group(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion Enteral nutrition support for patients with lung cancer chemotherapy can not only improve the nutritional status and immune function,but also reduce the risk of adverse reactions.

enteral nutrition supportlung cancerchemotherapynutritional statusimmune function

王真真、郝清源、刘敏

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驻马店市中心医院临床营养科,河南 驻马店,463000

肠内营养支持 肺癌 化疗 营养状态 免疫功能

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(34)