首页|腔镜与开放乳房皮下腺体切除术治疗早期乳腺癌患者的效果及对乳房美观度与复发情况的影响

腔镜与开放乳房皮下腺体切除术治疗早期乳腺癌患者的效果及对乳房美观度与复发情况的影响

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目的 探讨腔镜与开放乳房皮下腺体切除术治疗早期乳腺癌患者的效果及对乳房美观度、复发情况的影响。方法 选取 2021 年 4 月至 2023 年 4 月我院收治的 82 例早期乳腺癌患者,随机将其分为腔镜组(41例,腔镜乳房皮下腺体切除术)和开放组(41例,开放乳房皮下腺体切除术)。比较两组的治疗效果。结果 腔镜组的手术时长长于开放组,术中出血量少于开放组,引流管留置时长及住院时长短于开放组(P<0。05)。腔镜组的不良事件总发生率低于开放组(P<0。05)。术后,腔镜组的C-反应蛋白(CRP)、白细胞介素-8(IL-8)、癌胚抗原(CEA)、糖类抗原 15-3(CA15-3)及鳞状细胞癌抗原(SCC)水平低于开放组,白细胞介素-10(IL-10)水平、自然杀伤(NK)细胞及乳腺癌生存质量测评量表(FACT-B)评分高于开放组(P<0。05)。腔镜组的乳房美容满意度高于开放组(P<0。05)。结论 腔镜乳房皮下腺体切除术治疗早期乳腺癌患者的效果更佳。
Effect of endoscopic and open subcutaneous mastectomy in the treatment of patients with early breast cancer and their influences on breast aesthetics and recurrence
Objective To investigate the effect of endoscopic and open subcutaneous mastectomy in the treatment of patients with early breast cancer and their influences on breast aesthetics and recurrence.Methods A total of 82 patients with early breast cancer admitted in our hospital from April 2021 to April 2023 were selected and randomly divided into endoscopic group(41 cases,endoscopic subcutaneous mastectomy)and open group(41 cases,open subcutaneous mastectomy).The therapeutic effects of the two groups were compared.Results The operation time of the endoscopic group was longer than that of the open group,the intraoperative blood loss was less than that of the open group,and the drainage tube indwelling time and hospitalization time were shorter than those of the open group(P<0.05).The total incidence of adverse events in the endoscopic group was lower than that in the open group(P<0.05).After operation,the levels of C-reactive protein(CRP),interleukin-8(IL-8),carcino-embryonic antigen(CEA),carbohydrate antigen 15-3(CA15-3)and squamous cell carcinoma antigen(SCC)in the endoscopic group were lower than those in the open group,and interleukin-10(IL-10)level and natural killer(NK)cell and Functional Assessment of Cancer Therapy-Breast(FACT-B)score were higher than those in the open group(P<0.05).The satisfaction of breast beauty in the endoscopic group was higher than that in the open group(P<0.05).Conclusion Endoscopic subcutaneous mastectomy has better effect in the treatment of patients with early breast cancer.

breast cancerendoscopic subcutaneous mastectomyopen subcutaneous mastectomy

李慧、赵雪、马晓鑫

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河南科技大学第一附属医院乳腺外科,河南 洛阳,471000

乳腺癌 腔镜乳房皮下腺体切除术 开放乳房皮下腺体切除术

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(34)