首页|阴道镜下宫颈环形电切术对宫颈癌前病变患者性生活质量及术后并发症的影响

阴道镜下宫颈环形电切术对宫颈癌前病变患者性生活质量及术后并发症的影响

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目的 研究阴道镜下宫颈环形电切术对宫颈癌前病变患者性生活质量及术后并发症的影响。方法 选取2021年 10月至2022年11月我院收治的60例宫颈癌前病变患者,根据手术方案不同将其分为对照组和观察组,各 30例。对照组采用冷刀锥切术治疗,观察组采用阴道镜下宫颈环形电切术治疗。比较两组的临床疗效、临床相关指标、炎症指标、性激素指标、性生活质量及术后并发症发生情况。结果 观察组的治疗总有效率为96。67%,高于对照组的76。67%(P<0。05)。观察组的术中出血量少于对照组,手术时间、切口愈合时间、住院时间及阴道排液时间短于对照组(P<0。05)。术后7d,观察组的白细胞介素-2(IL-2)、γ-干扰素(IFN-γ)水平低于对照组,白细胞介素-4(IL-4)水平高于对照组(P<0。05)。术后7d,观察组的雌二醇(E2)水平高于对照组,卵泡刺激素(FSH)、黄体生成素(LH)水平低于对照组(P<0。05)。术后 3 个月,观察组的女性性功能指数量表(FSFI)评分高于对照组(P<0。05)。观察组的术后并发症总发生率低于对照组(P<0。05)。结论 阴道镜下宫颈环形电切术治疗宫颈癌前病变患者的效果显著,可改善性生活质量,降低术后并发症发生风险。
Effects of loop electrosurgical excisional procedure under colposcopy on quality of sexual life and postoperative complications in patients with precancerous lesions of uterine cervix
Objective To study the effects of loop electrosurgical excisional procedure under colposcopy on quality of sexual life and postoperative complications in patients with precancerous lesions of uterine cervix.Methods Sixty patients with precancerous lesions of uterine cervix admitted in our hospital from October 2021 to November 2022 were selected and divided into control group and observation group according to different surgical schemes,with 30 cases in each group.The control group was treated with cold knife conization,and the observation group was treated with loop electrosurgical excisional procedure under colposcopy.The clinical efficacy,clinical related indexes,inflammatory indexes,sex hormone indexes,quality of sexual life and postoperative complications were compared between the two groups.Results The total effective rate of treatment in the observation group was 96.67%,which was higher than 76.67%in the control group(P<0.05).The intraoperative blood loss in the observation group was less than that in the control group,and the operation time,incision healing time,hospitalization time and vaginal drainage time were shorter than those in the control group(P<0.05).At 7 d after operation,the levels of interleukin-2(IL-2)and interferon-γ(IFN-γ)in the observation group were lower than those in the control group,and the level of interleukin-4(IL-4)was higher than that in the control group(P<0.05).At 7 d after operation,the level of estradiol(E2)in the observation group was higher than that in the control group,and the levels of follicle stimulating hormone(FSH)and luteinizing hormone(LH)were lower than those in the control group(P<0.05).At 3 months after operation,the Female Sexual Function Index(FSFI)score in the observation group was higher than that in the control group(P<0.05).The total incidence of postoperative complications in the observation group was lower than that in the control group(P<0.05).Conclusion The loop electrosurgical excisional procedure under colposcopy in the treatment of patients with precancerous lesions of uterine cervix has a significant effect,which can improve the quality of sexual life and reduce the risk of postoperative complications.

precancerous lesions of uterine cervixcolposcopyloop electrosurgical excisional procedure

李静、曹菁

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宝鸡市陈仓医院妇科,陕西 宝鸡,721300

宫颈癌前病变 阴道镜 宫颈环形电切术

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(34)