Diagnostic value of electronic bronchoscopy combined with tumor markers screening for lung cancer
Objective To analyze the diagnostic value of electronic bronchoscopy combined with tumor markers screening for lung cancer,and to provide references for clinical diagnosis of lung cancer.Methods The clinical data of 106 patients with suspected lung cancer who were initially diagnosed in Hanzhong Central Hospital from August 2020 to August 2021 were retrospectively analyzed.According to the results of pathological biopsy,lung cancer patients were included in lung cancer group,and benign lesions were included in benign lesion group.The results of electronic bronchoscopy and the positive of tumor markers were compared between the two groups,and the diagnostic efficacy of single and combined detection of the two for lung cancer was analyzed.Results Among 106 patients with suspected lung cancer,85 cases were diagnosed as lung cancer and 21 cases were benign lesions by pathological biopsy.The positive rates of electronic bronchoscopy,carcino embryonic antigen(CEA),neuron-specific enolase(NSE),cytokeratin 19 fragment(CYFRA21-1)and squamous cell carcinoma antigen(SCCA)in the lung cancer group were higher than those in the benign lesion group,and the differences were statistically significant(P<0.05).The diagnostic sensitivity and accuracy of electronic bronchoscopy for lung cancer were lower than those of tumor markers screening,and the differences were statistically significant(P<0.05);the sensitivity,accuracy and negative predictive value of combined diagnosis for lung cancer were higher than those of electronic bronchoscopy,and the specificity,accuracy and positive predictive value were higher than those of tumor markers screening,and the differences were statistically significant(P<0.05).Conclusion Electronic bronchoscopy combined with tumor markers screening is helpful to improve the diagnostic efficiency of lung cancer,and the diagnostic efficiency of combined detection is better than that of single detection.
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