Analysis of infection status and drug resistance of pathogenic bacteria in a tertiary general hospital from 2019 to 2021
Objective To explore the current situation of hospital infection in 2019-2021,analyze the drug resistance of common pathogenic bacteria,and provide theoretical basis for the prevention and control of hospital infection.Methods The pathogenic specimens of patients who were hospitalized for more than 48 h in the clinical department of a tertiary general hospital from January 2019 to December 2021 were selected to analyze the occurrence of nosocomial infection,the types of pathogenic bacteria and the drug resistance of common pathogenic bacteria.Results The incidence of nosocomial infection in 2019-2021 was 1.52％,1.33％and 1.27％,respectively,showing a downward trend(P＜0.05);lower respiratory tract,upper respiratory tract and urinary tract were the common sites of nosocomial infection.The top five pathogens were Acinetobacter baumannii,Klebsiella pneumoniae,Pseudomonas aeruginosa,Staphylococcus aureus and Escherichia coli.Escherichia coli and Klebsiella pneumoniae had a high resistance rate(＞90％)to first generation cephalosporin antibiotics;the resistance rates of Pseudomonas aeruginosa to imipenem and aztreonam were high(39.18％-48.98％);the drug resistance situation of Acinetobacter baumannii was severe,and the drug resistance rate to multiple antibiotics was more than 50％;the resistance rate of Staphylococcus aureus to erythromycin fluctuated greatly(11.45％-68.08％),and the detection rate of methicillin-resistant Staphylococcus aureus(MRSA)was 51.92％-54.30％.Conclusion The overall hospital infection rate is showing a downward trend,and common pathogens have a high resistance rate to antibiotics.Acinetobacter baumannii has particularly severe resistance.It is necessary to continue to strengthen the rational use of antibiotics and the prevention and control of hospital infection,and control the production of multi-drug resistant strains.
万方数据
维普
