Predictive value of NLR,LMR and PLR for short-term outcomes in elderly patients with community acquired pneumonia
Objective To investigate the predictive effect of neutrophil to lymphocyte ratio(NLR),lymphocyte to monocyte ratio(LMR)and platelet to lymphocyte ratio(PLR)on 28 d survival outcome in elderly patients with community acquired pneumonia(CAP).Methods A total of 224 elderly patients with CAP who were hospitalized in the Second People's Hospital of Panyu from January to December 2022 and met the inclusion criteria were selected as the research objects.According to the severity of the disease,the patients were divided into mild group and severe group,with 112 cases in each group.The clinical data and inflammatory index of the patients were collected,including NLR,LMR,PLR,white blood cell count(WBC),platelet count(PLT),procalcitonin(PCT)and C-reactive protein(CRP)levels.The clinical data and inflammatory indexes levels of the two groups were compared;the relationship between LMR and other serum inflammatory markers was analyzed by Spearman correlation coefficient;the predictive value of NLR,LMR and PLR for survival outcome within 28 d in elderly patients with CAP was explored by receiver operating characteristic(ROC)curve.Results There were no significant differences in age,gender and basic diseases between the two groups(P＞0.05);the hospital stay in the severe group was longer than that in the mild group,and the difference was statistically significant(P＜0.05).The levels of NLR,PLR,WBC,PCT and CRP in the severe group were higher than those in the mild group,while LMR and PLT were lower than those in the mild group,and the differences were statistically significant(P＜0.01).LMR was negatively correlated with NLR,PLR,WBC,PCT and CRP(P＜0.01);there was no correlation between LMR and PLT(P=0.102).The 28 d survival outcome showed that there was no death in the mild group and 41 deaths in the severe group.The area under the curve(AUC)of NLR,LMR,PLR,PCT and CRP in predicting the risk of death in elderly patients with CAP was 0.854,0.710,0.731,0.768 and 0.830,respectively(P＜0.001).Conclusion NLR,LMR and PLR can be used to evaluate the severity of CAP in elderly patients and have predictive value for short-term outcomes.
community acquired pneumonianeutrophil to lymphocyte ratiolymphocyte to monocyte ratioplatelet to lymphocyte ratio
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