Correlation analysis of lactate dehydrogenase level and the occurrence of prolonged postoperative severe time in patients undergoing tricuspid valve surgery
Objective To explore the correlation between lactate dehydrogenase(LDH)level and the occurrence of prolonged postoperative severe time in patients undergoing tricuspid valve surgery.Methods The clinical data of 205 patients who underwent tricuspid valve surgery under extracorporeal circulation in our hospital from January 2018 to June 2019 were retrospectively analyzed.According to the LDH level,the patients were divided into low value group,median value group and high value group.Univariate and multivariate Logistic regression models combined with restricted cubic splines(RCS)model were used to explore the dose-response curve relationship and correlation between LDH level and prolonged postoperative severe time.The receiver operating characteristic(ROC)curve was used to evaluate the predictive value of LDH level for the occurrence of prolonged postoperative severe time.Results RCS analysis showed that there was a linear relationship between LDH and the risk of prolonged postoperative severe time(non-linear test P＞0.05).In multivariate adjusted model 2,for each standard deviation increase in LDH,the risk of prolonged postoperative severe time increased by 56％(P=0.029);the incidence of prolonged postoperative severe time in the high value group was 2.54 times higher than that in the low value group(P=0.036);the higher the LDH level,the higher the risk of prolonged postoperative severe time(P=0.021).The AUC of LDH level in predicting the occurrence of prolonged postoperative severe time was 0.701.Conclusion The higher LDH level is related to the increased risk of prolonged postoperative severe time,and has a good predictive value for the occurrence of prolonged postoperative severe time.
lactate dehydrogenaseintensive care timetricuspid valvecardiac surgical procedures
万方数据
维普
