Effects of early pregnancy medical nutrition therapy on islet function and HCY and APN levels in high-risk pregnant women with gestational diabetes mellitus
Objective To explore the effects of early pregnancy medical nutrition therapy on islet function and homocysteine(HCY)and adiponectin(APN)levels in high-risk pregnant women with gestational diabetes mellitus.Methods A total of 84 pregnant women with high risk of gestational diabetes mellitus admitted from January 2022 to January 2023 were randomly divided into control group and observation group,with 42 cases in each group.The control group was given routine pregnancy care guidance,and the observation group was given early pregnancy medical nutrition therapy on the basis of the control group.The therapeutic effects of the two groups were compared.Results After treatment,the levels of glycosylated hemoglobin(HbA1c),fasting plasma glucose(FPG),fructosamine(FMN)and fasting C peptide(FCP)in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).After treatment,the HCY level of the observation group was lower than that of the control group,and the APN level was higher than that of the control group,and the differences were statistically significant(P＜0.05).The total incidence of maternal and infant adverse outcomes in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Early pregnancy medical nutrition therapy can not only improve the islet function of high-risk pregnant women with gestational diabetes mellitus,regulate the levels of HCY and APN,but also reduce the risk of adverse maternal and infant outcomes,which is worthy of promotion.
early pregnancy medical nutrition therapygestational diabetes mellitushigh-risk pregnant womenislet functionhomocysteineadiponectin
万方数据
维普
