临床医学研究与实践2024,Vol.9Issue(35) :182-185.DOI:10.19347/j.cnki.2096-1413.202435046

脑小血管病内皮功能障碍的生物标志物研究进展

Research progress on biomarkers of endothelial dysfunction in cerebral small vessel disease

刘聪杰 肖艾妮 王翔宇
临床医学研究与实践2024,Vol.9Issue(35) :182-185.DOI:10.19347/j.cnki.2096-1413.202435046

脑小血管病内皮功能障碍的生物标志物研究进展

Research progress on biomarkers of endothelial dysfunction in cerebral small vessel disease

刘聪杰 1肖艾妮 1王翔宇1
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作者信息

  • 1. 三峡大学第三临床医学院/国药葛洲坝中心医院神经内科,湖北宜昌,443000
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摘要

随着世界人口老龄化的加剧,脑小血管病(CSVD)发病率逐渐升高,对人们的生活和健康造成了极大威胁.该病隐匿,临床症状各异,易被忽略,同时缺乏有效的治疗手段.相关研究证明,内皮功能障碍参与了CSVD的发生与发展过程.本文旨在对CSVD的发病机制——内皮功能障碍的生物标志物进行综述,进一步探究CSVD的危险因素及其作用机制,为临床诊疗提供参考和新思路.

Abstract

With the aging of the world's population,the incidence of cerebral small vessel disease(CSVD)has gradually increased,posing a great threat to people's lives and health.The disease is hidden,has different clinical symptoms,and is easily ignored.At the same time,there is a lack of effective treatment.Relevant studies have proven that endothelial dysfunction is involved in the occurrence and development of CSVD.This article aims to review the pathogenesis of CSVD-biomarkers of endothelial dysfunction,further explore the risk factors of CSVD and its mechanism of action,and provide reference and new ideas for clinical diagnosis and treatment.

关键词

脑小血管病/内皮功能障碍/生物标志物

Key words

cerebral small vessel disease/endothelial dysfunction/biomarker

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出版年

2024
临床医学研究与实践

临床医学研究与实践

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