Correlation between thrombelastogram and pediatric sepsis 3.0 scoring criteria
Objective To investigate the correlation between thromboelastogram(TEG)and pediatric sepsis 3.0 scoring criteria.Methods The clinical data of 51 children with sepsis admitted to PICU of Weifang Maternal and Child Health Hospital from January 2021 to December 2023 were retrospectively analyzed.According to the Phoenix Sepsis Score(PSS),the children were divided into sepsis group(n=40)and septic shock group(n=11).Routine blood test,TEG test and PSS score were completed within 24 h after admission.The TEG indexes of the two groups were compared;Spearman correlation analysis was used to explore the correlation between TEG indicators and PSS scores.Results The PSS score of the sepsis group was lower than that of the septic shock group,and the difference was statistically significant(P＜0.05).The reaction time(R)and kinetics time(K)of the sepsis group were shorter than those of the septic shock group,and the αangle,maximum amplitude(MA)and coagulation index(Cl)were higher than those of the control group,the differences were statistically significant(P＜0.05).Spearman correlation analysis showed that PSS score was positively correlated with R and K(r=0.908,0.681,P＜0.001);PSS score was negatively correlated with αangle,MA and CI(r=-0.869,-0.690,-0.901,P＜0.001).Conclusion TEG has a clear correlation with PSS score of sepsis in children,and has a reference value for predicting the severity of sepsis in children.It has a certain predictive value for the condition of children with septic shock,and has certain significance for formulating intervention measures in advance and improving the success rate of rescue.
万方数据
维普
