首页|布地奈德混悬液雾化联合咽鼓管吹张治疗儿童分泌性中耳炎的临床效果

布地奈德混悬液雾化联合咽鼓管吹张治疗儿童分泌性中耳炎的临床效果

扫码查看
目的 探究布地奈德混悬液雾化联合咽鼓管吹张治疗儿童分泌性中耳炎(OME)的临床效果。方法 选取2021年4月至2022年12月就诊于我院的108例OME患儿为研究对象,按照随机硬币抛掷法将其分为对照组(53例,85耳)和观察组(55例,90耳)。对照组给予咽鼓管吹张治疗,观察组在对照组基础上给予布地奈德混悬液雾化治疗。比较两组的治疗效果。结果 治疗后,观察组的耳闷胀感、耳鸣、听力下降及中耳积液评分低于对照组(P<0。05)。治疗后,观察组的气导听阈、气骨导差低于对照组(P<0。05)。治疗后,观察组的免疫球蛋白E(lgE)、白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)水平低于对照组(P<0。05)。观察组的治疗总有效率为94。44%(85/90),高于对照组的80。00%(68/85)(P<0。05)。结论 布地奈德混悬液雾化联合咽鼓管吹张治疗能有效改善OME患儿临床症状,降低机体免疫炎症反应,提高听力水平,增强临床治疗效果。
Clinical effect of budesonide suspension atomization combined with eustachian tube blowing in the treatment of otitis media with effusion in children
Objective To explore the clinical effect of budesonide suspension atomization combined with eustachian tube blowing in the treatment of otitis media with effusion(OME)in children.Methods A total of 108 children with OME who were treated in our hospital from April 2021 to December 2022 were selected as the research objects.According to the random coin toss method,the children were divided into control group(53 cases,85 ears)and observation group(55 cases,90 ears).The control group was treated with eustachian tube blowing,and the observation group was treated with budesonide suspension atomization on the basis of the control group.The therapeutic effects of the two groups were compared.Results After treatment,the scores of ear fullness,tinnitus,hearing loss and middle ear effusion in the observation group were lower than those in the control group(P<0.05).After treatment,the air conduction hearing threshold and air-bone gap in the observation group were lower than those in the control group(P<0.05).After treatment,the levels of immunoglobulin E(IgE),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)in the observation group were lower than those in the control group(P<0.05).The total effective rate of treatment in the observation group was 94.44%(85/90),which was higher than 80.00%(68/85)in the control group(P<0.05).Conclusion Budesonide suspension atomization combined with eustachian tube blowing therapy can effectively improve the clinical symptoms of children with OME,reduce the body's immune inflammatory response,improve the hearing level and enhance the clinical treatment effect.

otitis media with effusionchildrenbudesonide suspensionatomizationeustachian tube blowing

高旭栋、丁瑜

展开 >

陕西省人民医院耳鼻咽喉头颈外科,陕西西安,710068

分泌性中耳炎 儿童 布地奈德混悬液 雾化 咽鼓管吹张

2024

临床医学研究与实践

临床医学研究与实践

ISSN:
年,卷(期):2024.9(36)